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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
10
Human Site:
T623
Identified Species:
22
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
T623
D
P
R
L
T
F
S
T
L
E
L
R
D
I
P
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
T623
D
P
R
L
T
F
S
T
L
E
L
R
D
I
P
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
S599
T
G
S
R
S
P
L
S
R
L
R
Q
R
A
L
Dog
Lupus familis
XP_534913
800
89979
R623
R
L
R
P
Q
A
L
R
R
D
P
R
L
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
S623
R
D
P
R
L
T
F
S
T
L
E
L
R
D
V
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
L834
I
T
P
T
S
E
L
L
P
L
G
P
V
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
S320
R
Q
L
L
L
E
G
S
M
R
M
K
E
G
K
Chicken
Gallus gallus
XP_423692
451
48811
L299
A
E
E
G
P
E
A
L
A
P
R
P
P
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
S601
D
L
D
P
E
S
R
S
L
S
I
D
S
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
S605
I
P
K
T
P
R
G
S
S
R
A
S
R
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
Q676
V
M
N
G
T
G
V
Q
E
N
N
S
N
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
0
13.3
N.A.
0
0
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
20
20
N.A.
6.6
6.6
N.A.
40
13.3
N.A.
26.6
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
10
0
10
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
10
10
0
0
0
0
0
0
10
0
10
19
19
0
% D
% Glu:
0
10
10
0
10
28
0
0
10
19
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
19
0
10
19
0
0
0
10
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
0
0
10
0
0
19
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
19
10
28
19
0
28
19
28
28
19
10
10
0
10
% L
% Met:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
10
0
10
10
0
% N
% Pro:
0
28
19
19
19
10
0
0
10
10
10
19
10
0
28
% P
% Gln:
0
10
0
0
10
0
0
10
0
0
0
10
0
0
10
% Q
% Arg:
28
0
28
19
0
10
10
10
19
19
19
28
28
0
0
% R
% Ser:
0
0
10
0
19
10
19
46
10
10
0
19
10
10
10
% S
% Thr:
10
10
0
19
28
10
0
19
10
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _