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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
23.33
Human Site:
Y263
Identified Species:
51.33
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
Y263
R
F
H
P
Y
V
Q
Y
C
L
R
V
K
Q
T
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
Y263
R
F
H
P
Y
V
Q
Y
C
L
R
V
K
Q
T
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
Y263
R
F
H
P
Y
V
Q
Y
C
L
R
V
K
Q
T
Dog
Lupus familis
XP_534913
800
89979
Y263
R
F
Q
P
Y
V
Q
Y
C
L
Q
V
K
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
Y263
R
F
Q
P
Y
V
Q
Y
C
L
R
V
K
Q
T
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
Y474
L
F
K
P
Y
I
R
Y
C
M
E
E
E
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
Chicken
Gallus gallus
XP_423692
451
48811
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
Y241
R
F
K
P
Y
I
R
Y
C
M
E
E
E
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
R273
L
A
M
I
N
T
S
R
T
T
G
Q
P
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
F322
Q
F
S
A
Y
F
K
F
C
A
E
E
D
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
100
80
N.A.
93.3
33.3
N.A.
0
0
N.A.
40
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
60
N.A.
0
0
N.A.
66.6
N.A.
N.A.
0
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
28
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
28
28
19
0
10
% E
% Phe:
0
73
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
19
0
% G
% His:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
0
0
0
10
0
0
0
0
0
46
0
0
% K
% Leu:
19
0
0
0
0
0
0
0
0
46
0
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
19
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
64
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
19
0
0
0
46
0
0
0
10
10
0
37
0
% Q
% Arg:
55
0
0
0
0
0
19
10
0
0
37
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
46
% T
% Val:
0
0
0
0
0
46
0
0
0
0
0
46
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
73
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _