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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG6
All Species:
19.09
Human Site:
Y373
Identified Species:
42
UniProt:
Q3KR16
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3KR16
NP_001138328.1
790
88961
Y373
A
A
Q
R
I
G
P
Y
E
V
L
E
P
P
S
Chimpanzee
Pan troglodytes
XP_001160991
790
89043
Y373
A
A
Q
R
I
G
P
Y
E
V
L
E
P
P
S
Rhesus Macaque
Macaca mulatta
XP_001118229
751
83748
P372
A
A
A
Q
R
I
G
P
Y
E
V
L
E
P
P
Dog
Lupus familis
XP_534913
800
89979
Y373
A
A
Q
R
I
G
P
Y
E
V
L
E
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0J1
787
89106
Y373
V
A
Q
R
I
G
P
Y
E
V
L
E
P
S
S
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
Y584
V
V
S
R
I
D
A
Y
E
V
V
E
G
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
L93
R
V
I
T
D
L
F
L
C
C
L
L
N
L
Q
Chicken
Gallus gallus
XP_423692
451
48811
Q72
M
R
Q
R
Q
E
Q
Q
R
L
A
A
I
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
Y351
I
A
G
R
I
E
A
Y
E
A
V
E
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
T375
E
E
Q
R
A
E
L
T
H
M
I
K
S
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782471
866
97476
V437
G
I
L
E
G
Y
E
V
P
N
A
P
T
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
83.6
80.5
N.A.
81.1
32.4
N.A.
31.1
20.6
N.A.
33.1
N.A.
N.A.
26.4
N.A.
21.4
Protein Similarity:
100
99.8
86.3
87.5
N.A.
88.2
45.2
N.A.
43.1
34
N.A.
50.5
N.A.
N.A.
44.4
N.A.
40.3
P-Site Identity:
100
100
20
93.3
N.A.
86.6
40
N.A.
6.6
20
N.A.
46.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
33.3
93.3
N.A.
86.6
53.3
N.A.
6.6
26.6
N.A.
53.3
N.A.
N.A.
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
55
10
0
10
0
19
0
0
10
19
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
10
0
10
0
28
10
0
55
10
0
55
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
37
10
0
0
0
0
0
19
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
55
10
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
10
0
0
10
10
10
0
10
46
19
0
19
0
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
37
10
10
0
0
10
37
28
10
% P
% Gln:
0
0
55
10
10
0
10
10
0
0
0
0
0
0
10
% Q
% Arg:
10
10
0
73
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
10
28
55
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
19
19
0
0
0
0
0
10
0
46
28
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _