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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAK All Species: 14.85
Human Site: S363 Identified Species: 27.22
UniProt: Q3LXA3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3LXA3 NP_056348.2 575 58977 S363 E P Q E A P D S T A A G G S A
Chimpanzee Pan troglodytes XP_522025 621 64151 S409 E P Q E A P D S T A A G G S A
Rhesus Macaque Macaca mulatta XP_001082829 524 54569 S312 E P Q E A L D S T A V G G S A
Dog Lupus familis XP_540921 578 59438 S363 E P L E A P D S T A A E G L P
Cat Felis silvestris
Mouse Mus musculus Q8VC30 578 59673 A363 E P P E A P E A T A A G G V T
Rat Rattus norvegicus Q4KLZ6 578 59425 A363 E P A E A P E A T A A G G V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507653 603 61888 P388 E R P R A E E P A A S E G P A
Chicken Gallus gallus XP_424258 405 41742 L215 L A R V C S T L L G L Q D K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070098 576 59741 K364 K S A A A S D K C S E G A L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002329708 595 61950 S369 H S G K S D E S L S R P Q Q L
Maize Zea mays NP_001148575 594 61687 E368 S P S M K D D E I L A P S Q E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188404 595 61902 E379 R P L E L S K E G Q V L E A A
Baker's Yeast Sacchar. cerevisiae P54838 584 62188 T376 D L L H N E V T A K A V G T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 75.3 90.8 N.A. 84.7 85.2 N.A. 78.6 51.6 N.A. 56 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 78.9 95.3 N.A. 92.5 92.5 N.A. 86.9 60 N.A. 73.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 66.6 73.3 N.A. 33.3 0 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 73.3 N.A. 80 86.6 N.A. 46.6 6.6 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 39.8 41.5 N.A. 41.3 35.6 N.A.
Protein Similarity: 59.1 59.7 N.A. 58.6 53 N.A.
P-Site Identity: 6.6 20 N.A. 20 13.3 N.A.
P-Site Similarity: 33.3 20 N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 8 62 0 0 16 16 54 54 0 8 8 47 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 16 47 0 0 0 0 0 8 0 0 % D
% Glu: 54 0 0 54 0 16 31 16 0 0 8 16 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 8 8 0 47 62 0 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 8 0 0 8 8 0 8 8 0 8 0 0 0 8 0 % K
% Leu: 8 8 24 0 8 8 0 8 16 8 8 8 0 16 16 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 62 16 0 0 39 0 8 0 0 0 16 0 8 8 % P
% Gln: 0 0 24 0 0 0 0 0 0 8 0 8 8 16 0 % Q
% Arg: 8 8 8 8 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 16 8 0 8 24 0 39 0 16 8 0 8 24 8 % S
% Thr: 0 0 0 0 0 0 8 8 47 0 0 0 0 8 8 % T
% Val: 0 0 0 8 0 0 8 0 0 0 16 8 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _