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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAK All Species: 36.36
Human Site: S409 Identified Species: 66.67
UniProt: Q3LXA3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3LXA3 NP_056348.2 575 58977 S409 G D C G T T H S R A A R A I Q
Chimpanzee Pan troglodytes XP_522025 621 64151 S455 G D C G T T H S R A A R A I Q
Rhesus Macaque Macaca mulatta XP_001082829 524 54569 S358 G D C G T T H S R A A R A I R
Dog Lupus familis XP_540921 578 59438 S409 G D C G T T H S R A A R A I Q
Cat Felis silvestris
Mouse Mus musculus Q8VC30 578 59673 S409 G D C G S T H S R A A K A I Q
Rat Rattus norvegicus Q4KLZ6 578 59425 S409 G D C G S T H S R A A K A I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507653 603 61888 S434 G D C G T T H S R A A R A I R
Chicken Gallus gallus XP_424258 405 41742 L254 E W M R A Q P L P P S P A H L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070098 576 59741 A409 G G C G S T H A L V A N V I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002329708 595 61950 Y418 G D C G S T M Y R G A T A I L
Maize Zea mays NP_001148575 594 61687 Y418 G D C G S T M Y R G A T A I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188404 595 61902 Y418 G D C G S T M Y R G A T A I L
Baker's Yeast Sacchar. cerevisiae P54838 584 62188 V423 G D C G Y T L V A G V K G I T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 75.3 90.8 N.A. 84.7 85.2 N.A. 78.6 51.6 N.A. 56 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 78.9 95.3 N.A. 92.5 92.5 N.A. 86.9 60 N.A. 73.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 86.6 86.6 N.A. 93.3 6.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 39.8 41.5 N.A. 41.3 35.6 N.A.
Protein Similarity: 59.1 59.7 N.A. 58.6 53 N.A.
P-Site Identity: 60 60 N.A. 60 40 N.A.
P-Site Similarity: 66.6 66.6 N.A. 66.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 54 85 0 85 0 0 % A
% Cys: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 93 8 0 93 0 0 0 0 0 31 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 62 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 8 8 0 0 0 0 0 31 % L
% Met: 0 0 8 0 0 0 24 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 8 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 47 % Q
% Arg: 0 0 0 8 0 0 0 0 77 0 0 39 0 0 16 % R
% Ser: 0 0 0 0 47 0 0 54 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 39 93 0 0 0 0 0 24 0 0 8 % T
% Val: 0 0 0 0 0 0 0 8 0 8 8 0 8 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 24 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _