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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LSM12
All Species:
14.24
Human Site:
S175
Identified Species:
34.81
UniProt:
Q3MHD2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MHD2
NP_689557.1
195
21701
S175
K
H
F
R
D
V
E
S
Q
K
I
L
Q
R
S
Chimpanzee
Pan troglodytes
XP_523664
244
26749
S224
K
H
F
R
D
V
E
S
Q
K
I
L
Q
R
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513336
87
9725
Y68
E
V
I
I
A
P
P
Y
Q
V
E
N
C
K
G
Chicken
Gallus gallus
Q5ZML5
194
21501
S174
K
H
F
R
D
V
E
S
Q
K
V
M
Q
R
S
Frog
Xenopus laevis
Q6GP89
194
21480
N174
K
H
F
R
D
V
E
N
Q
K
G
V
Q
R
N
Zebra Danio
Brachydanio rerio
Q6PBA2
196
21593
S176
K
H
F
R
D
V
E
S
Q
K
T
M
Q
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYR0
217
23727
R183
I
K
Q
F
F
N
T
R
P
S
P
V
P
E
S
Honey Bee
Apis mellifera
XP_392005
198
21838
A176
K
H
I
K
D
T
E
A
S
Q
Q
A
Q
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795140
125
14209
P106
E
D
V
H
V
I
P
P
Y
T
A
A
C
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38828
187
21295
Q168
N
Q
S
I
T
L
I
Q
R
I
V
E
R
S
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
93.8
81.5
85.1
N.A.
29.4
46.9
N.A.
26.6
Protein Similarity:
100
78.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
44
96.4
91.2
94.3
N.A.
50.2
63.1
N.A.
38.9
P-Site Identity:
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
86.6
73.3
86.6
N.A.
6.6
33.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
100
93.3
93.3
N.A.
13.3
60
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
10
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
0
% C
% Asp:
0
10
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
0
0
0
60
0
0
0
10
10
0
10
0
% E
% Phe:
0
0
50
10
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
60
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
20
20
0
10
10
0
0
10
20
0
0
0
0
% I
% Lys:
60
10
0
10
0
0
0
0
0
50
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
10
0
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
10
20
10
10
0
10
0
10
0
0
% P
% Gln:
0
10
10
0
0
0
0
10
60
10
10
0
60
10
10
% Q
% Arg:
0
0
0
50
0
0
0
10
10
0
0
0
10
50
0
% R
% Ser:
0
0
10
0
0
0
0
40
10
10
0
0
0
10
60
% S
% Thr:
0
0
0
0
10
10
10
0
0
10
10
0
0
0
0
% T
% Val:
0
10
10
0
10
50
0
0
0
10
20
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _