KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D25
All Species:
17.58
Human Site:
S567
Identified Species:
38.67
UniProt:
Q3MII6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MII6
NP_002527.1
688
76357
S567
P
S
S
S
S
P
P
S
T
Q
E
A
S
P
T
Chimpanzee
Pan troglodytes
XP_001139235
548
60665
G472
L
P
P
P
Q
E
F
G
R
G
N
P
F
M
L
Rhesus Macaque
Macaca mulatta
XP_001098742
688
76366
S567
P
S
S
S
S
P
P
S
T
Q
E
P
S
P
T
Dog
Lupus familis
XP_548985
687
76023
S566
P
S
S
S
S
P
P
S
T
Q
E
A
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
A1A5B6
742
82556
S621
P
S
S
S
S
P
P
S
T
Q
E
A
S
P
S
Rat
Rattus norvegicus
NP_001100425
688
76364
S567
P
S
S
S
S
P
P
S
T
Q
E
A
S
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520975
664
74736
P557
P
S
S
P
S
H
S
P
F
G
P
V
S
P
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121708
863
95814
A694
K
S
P
S
L
P
K
A
F
S
S
N
L
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611029
1098
122546
P982
E
S
A
Y
T
R
S
P
Q
R
S
T
H
L
N
Honey Bee
Apis mellifera
XP_395220
875
99616
E593
K
I
T
P
S
D
A
E
P
E
L
R
R
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192002
715
80854
K555
T
S
L
A
F
Y
Q
K
S
S
D
D
L
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.1
99.2
94.7
N.A.
87.1
93.5
N.A.
66.7
N.A.
N.A.
56.6
N.A.
27.1
37
N.A.
43.3
Protein Similarity:
100
78.7
99.7
97
N.A.
88.8
95.3
N.A.
75.4
N.A.
N.A.
64.7
N.A.
38.3
50.9
N.A.
59.4
P-Site Identity:
100
0
93.3
93.3
N.A.
93.3
93.3
N.A.
40
N.A.
N.A.
26.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
0
93.3
93.3
N.A.
100
100
N.A.
40
N.A.
N.A.
40
N.A.
26.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
10
0
0
0
37
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
10
0
10
46
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
19
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
10
0
0
0
0
0
10
0
19
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% N
% Pro:
55
10
19
28
0
55
46
19
10
0
10
19
0
64
10
% P
% Gln:
0
0
0
0
10
0
10
0
10
46
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
10
0
10
10
0
0
% R
% Ser:
0
82
55
55
64
0
19
46
10
19
19
0
55
0
37
% S
% Thr:
10
0
10
0
10
0
0
0
46
0
0
10
0
10
28
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _