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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPRIPL2
All Species:
15.76
Human Site:
S247
Identified Species:
43.33
UniProt:
Q3MIP1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MIP1
NP_001030013.1
535
58446
S247
V
R
G
R
R
H
L
S
A
T
L
V
L
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083619
535
58415
S247
V
R
G
R
R
H
L
S
A
T
L
V
L
R
W
Dog
Lupus familis
XP_854429
786
89240
Y406
L
E
S
F
Y
K
H
Y
V
Q
N
V
T
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV16
535
58647
S247
V
Q
G
R
R
H
L
S
A
T
L
V
L
R
W
Rat
Rattus norvegicus
Q66H52
547
62530
S302
I
K
A
A
L
C
T
S
S
H
L
D
V
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509288
551
59870
S272
L
R
G
R
P
H
L
S
S
G
L
V
L
R
W
Chicken
Gallus gallus
XP_001234851
419
45923
A207
M
A
V
R
L
I
P
A
I
P
L
G
D
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683287
486
55046
K222
H
S
S
Q
N
V
Y
K
M
S
P
D
S
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648203
346
40275
K139
T
T
S
N
R
V
Y
K
L
T
Y
T
L
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
20.8
N.A.
85.6
21.9
N.A.
61.7
41.5
N.A.
40.3
N.A.
20.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.8
31.9
N.A.
89.1
35.4
N.A.
70.9
53
N.A.
54.3
N.A.
32.5
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
13.3
N.A.
93.3
13.3
N.A.
73.3
13.3
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
100
40
N.A.
86.6
26.6
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
0
0
0
12
34
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
23
12
0
12
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
45
0
0
0
0
0
0
12
0
12
0
0
12
% G
% His:
12
0
0
0
0
45
12
0
0
12
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
12
0
23
0
0
0
0
0
0
12
% K
% Leu:
23
0
0
0
23
0
45
0
12
0
67
0
56
0
12
% L
% Met:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
12
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
12
0
0
12
12
0
0
0
0
% P
% Gln:
0
12
0
12
0
0
0
0
0
12
0
0
0
0
12
% Q
% Arg:
0
34
0
56
45
0
0
0
0
0
0
0
0
56
0
% R
% Ser:
0
12
34
0
0
0
0
56
23
12
0
0
12
0
0
% S
% Thr:
12
12
0
0
0
0
12
0
0
45
0
12
12
0
0
% T
% Val:
34
0
12
0
0
23
0
0
12
0
0
56
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% W
% Tyr:
0
0
0
0
12
0
23
12
0
0
12
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _