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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK5 All Species: 5.76
Human Site: S24 Identified Species: 9.74
UniProt: Q3MIX3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MIX3 NP_777582.3 580 65897 S24 R R Q K P W P S P A V F F R R
Chimpanzee Pan troglodytes XP_001157317 580 65781 S24 S R Q K P W P S P A A F F R R
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 S25 A S G I Y L Y S N K Y L D P N
Dog Lupus familis XP_539216 624 71219 P67 S T L D P W L P P A A F P R R
Cat Felis silvestris
Mouse Mus musculus Q80V03 582 66636 C24 S R Q K P W P C P A I F F R R
Rat Rattus norvegicus NP_001129270 582 66734 C24 S R Q K P W P C P A I F F R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507044 482 54419 V31 Y R E A R A L V F S L S L G V
Chicken Gallus gallus Q5ZMT7 519 59182 Y21 A A S G I Y L Y G N K F M D P
Frog Xenopus laevis Q6INL7 520 59525 G20 S V S L S S S G F F L Y G T G
Zebra Danio Brachydanio rerio XP_001341554 579 66788 I26 L R K C P R L I A P Q V F H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648446 557 64196 K20 L G T R I R G K R A L N G L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181542 582 67255 N33 L C R H M I K N P S A L T R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 S24 G T A L C G G S G A A F I A S
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 Q27 R T G K S I P Q R S P R T R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 34.4 77 N.A. 80.5 79.3 N.A. 56.2 32.2 32.9 60.5 N.A. 38.9 N.A. N.A. 41.4
Protein Similarity: 100 99.6 51.7 83.3 N.A. 89 88.1 N.A. 63.7 49.6 51.5 76.5 N.A. 57.2 N.A. N.A. 60.4
P-Site Identity: 100 86.6 6.6 46.6 N.A. 80 80 N.A. 6.6 6.6 0 20 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 86.6 6.6 46.6 N.A. 86.6 86.6 N.A. 26.6 13.3 13.3 33.3 N.A. 26.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 51.7 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 20 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 8 0 8 0 0 8 50 29 0 0 8 0 % A
% Cys: 0 8 0 8 8 0 0 15 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 15 8 0 50 36 0 0 % F
% Gly: 8 8 15 8 0 8 15 8 15 0 0 0 15 8 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 15 15 0 8 0 0 15 0 8 0 0 % I
% Lys: 0 0 8 36 0 0 8 8 0 8 8 0 0 0 8 % K
% Leu: 22 0 8 15 0 8 29 0 0 0 22 15 8 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 8 0 8 0 0 8 % N
% Pro: 0 0 0 0 43 0 36 8 43 8 8 0 8 8 8 % P
% Gln: 0 0 29 0 0 0 0 8 0 0 8 0 0 0 8 % Q
% Arg: 15 43 8 8 8 15 0 0 15 0 0 8 0 50 43 % R
% Ser: 36 8 15 0 15 8 8 29 0 22 0 8 0 0 8 % S
% Thr: 0 22 8 0 0 0 0 0 0 0 0 0 15 8 0 % T
% Val: 0 8 0 0 0 0 0 8 0 0 8 8 0 0 15 % V
% Trp: 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 8 8 8 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _