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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK5 All Species: 26.36
Human Site: S309 Identified Species: 44.62
UniProt: Q3MIX3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MIX3 NP_777582.3 580 65897 S309 R V H W D K S S K R V L T A D
Chimpanzee Pan troglodytes XP_001157317 580 65781 S309 R V H W D K S S K R V L T A D
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 N272 F V D G G Q V N D R D Y M E K
Dog Lupus familis XP_539216 624 71219 S353 R V H W D T S S K R V L T A E
Cat Felis silvestris
Mouse Mus musculus Q80V03 582 66636 S309 R V H W D R S S K R V L T A D
Rat Rattus norvegicus NP_001129270 582 66734 S309 R V Y W D K S S K R V L T A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507044 482 54419 T279 K A K L Q D G T E V A V K V Q
Chicken Gallus gallus Q5ZMT7 519 59182 N269 F M E G G Q V N D K A Y M E K
Frog Xenopus laevis Q6INL7 520 59525 M266 R V L V M E Y M E G G Q V N D
Zebra Danio Brachydanio rerio XP_001341554 579 66788 S309 K V F W D V T S K R V L T A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648446 557 64196 K283 K V H W S Y T K T R V L T L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181542 582 67255 N345 K V Y W N L T N K R I L T M E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 T273 T I Y W N L S T S K L L T M E
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 H292 I P K V I E S H K R I L I M E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 34.4 77 N.A. 80.5 79.3 N.A. 56.2 32.2 32.9 60.5 N.A. 38.9 N.A. N.A. 41.4
Protein Similarity: 100 99.6 51.7 83.3 N.A. 89 88.1 N.A. 63.7 49.6 51.5 76.5 N.A. 57.2 N.A. N.A. 60.4
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 93.3 N.A. 0 0 20 66.6 N.A. 46.6 N.A. N.A. 40
P-Site Similarity: 100 100 26.6 93.3 N.A. 100 100 N.A. 26.6 26.6 33.3 86.6 N.A. 66.6 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 51.7 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 15 0 0 43 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 43 8 0 0 15 0 8 0 0 0 36 % D
% Glu: 0 0 8 0 0 15 0 0 15 0 0 0 0 15 43 % E
% Phe: 15 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 15 15 0 8 0 0 8 8 0 0 0 0 % G
% His: 0 0 36 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 8 0 0 0 0 0 15 0 8 0 0 % I
% Lys: 29 0 15 0 0 22 0 8 58 15 0 0 8 0 15 % K
% Leu: 0 0 8 8 0 15 0 0 0 0 8 72 0 8 0 % L
% Met: 0 8 0 0 8 0 0 8 0 0 0 0 15 22 0 % M
% Asn: 0 0 0 0 15 0 0 22 0 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 15 0 0 0 0 0 8 0 0 8 % Q
% Arg: 43 0 0 0 0 8 0 0 0 72 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 0 50 43 8 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 8 22 15 8 0 0 0 65 0 0 % T
% Val: 0 72 0 15 0 8 15 0 0 8 50 8 8 8 0 % V
% Trp: 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 22 0 0 8 8 0 0 0 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _