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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK5 All Species: 9.7
Human Site: S42 Identified Species: 16.41
UniProt: Q3MIX3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MIX3 NP_777582.3 580 65897 S42 G L P P R F S S P T P L W R K
Chimpanzee Pan troglodytes XP_001157317 580 65781 S42 G L P P R F S S P T P L W R K
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 T45 R V G R A V A T T A V I S Y D
Dog Lupus familis XP_539216 624 71219 R86 L P T R W P L R P K P L W R K
Cat Felis silvestris
Mouse Mus musculus Q80V03 582 66636 R42 S P P A R T S R A R L L W R R
Rat Rattus norvegicus NP_001129270 582 66734 R42 S P L A R T S R T R L L W R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507044 482 54419 G47 P L P G E L E G V T E P P V D
Chicken Gallus gallus Q5ZMT7 519 59182 T42 R V G R A I A T T A V I T Y D
Frog Xenopus laevis Q6INL7 520 59525 V36 W D P S D F G V V R I G R A V
Zebra Danio Brachydanio rerio XP_001341554 579 66788 K42 F S S N R V V K G H R L F R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648446 557 64196 R36 A N V Q K G G R P V L R F S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181542 582 67255 S57 S L L A L R T S I G H A S V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900 I45 T L K L C T S I P V R L Y R N
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 S44 L V G G T I A S A V V L Y N F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 34.4 77 N.A. 80.5 79.3 N.A. 56.2 32.2 32.9 60.5 N.A. 38.9 N.A. N.A. 41.4
Protein Similarity: 100 99.6 51.7 83.3 N.A. 89 88.1 N.A. 63.7 49.6 51.5 76.5 N.A. 57.2 N.A. N.A. 60.4
P-Site Identity: 100 100 0 40 N.A. 40 33.3 N.A. 20 0 13.3 26.6 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 26.6 40 N.A. 46.6 40 N.A. 20 26.6 13.3 33.3 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 51.7 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 22 15 0 22 0 15 15 0 8 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 22 % D
% Glu: 0 0 0 0 8 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 8 0 0 0 0 22 0 0 0 0 0 0 15 0 8 % F
% Gly: 15 0 22 15 0 8 15 8 8 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 0 8 8 0 8 15 0 0 0 % I
% Lys: 0 0 8 0 8 0 0 8 0 8 0 0 0 0 36 % K
% Leu: 15 36 15 8 8 8 8 0 0 0 22 58 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 0 0 8 8 % N
% Pro: 8 22 36 15 0 8 0 0 36 0 22 8 8 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 22 36 8 0 29 0 22 15 8 8 50 15 % R
% Ser: 22 8 8 8 0 0 36 29 0 0 0 0 15 8 0 % S
% Thr: 8 0 8 0 8 22 8 15 22 22 0 0 8 0 0 % T
% Val: 0 22 8 0 0 15 8 8 15 22 22 0 0 15 8 % V
% Trp: 8 0 0 0 8 0 0 0 0 0 0 0 36 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 15 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _