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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK5
All Species:
9.7
Human Site:
S42
Identified Species:
16.41
UniProt:
Q3MIX3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MIX3
NP_777582.3
580
65897
S42
G
L
P
P
R
F
S
S
P
T
P
L
W
R
K
Chimpanzee
Pan troglodytes
XP_001157317
580
65781
S42
G
L
P
P
R
F
S
S
P
T
P
L
W
R
K
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
T45
R
V
G
R
A
V
A
T
T
A
V
I
S
Y
D
Dog
Lupus familis
XP_539216
624
71219
R86
L
P
T
R
W
P
L
R
P
K
P
L
W
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80V03
582
66636
R42
S
P
P
A
R
T
S
R
A
R
L
L
W
R
R
Rat
Rattus norvegicus
NP_001129270
582
66734
R42
S
P
L
A
R
T
S
R
T
R
L
L
W
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507044
482
54419
G47
P
L
P
G
E
L
E
G
V
T
E
P
P
V
D
Chicken
Gallus gallus
Q5ZMT7
519
59182
T42
R
V
G
R
A
I
A
T
T
A
V
I
T
Y
D
Frog
Xenopus laevis
Q6INL7
520
59525
V36
W
D
P
S
D
F
G
V
V
R
I
G
R
A
V
Zebra Danio
Brachydanio rerio
XP_001341554
579
66788
K42
F
S
S
N
R
V
V
K
G
H
R
L
F
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648446
557
64196
R36
A
N
V
Q
K
G
G
R
P
V
L
R
F
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181542
582
67255
S57
S
L
L
A
L
R
T
S
I
G
H
A
S
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
I45
T
L
K
L
C
T
S
I
P
V
R
L
Y
R
N
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
S44
L
V
G
G
T
I
A
S
A
V
V
L
Y
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34.4
77
N.A.
80.5
79.3
N.A.
56.2
32.2
32.9
60.5
N.A.
38.9
N.A.
N.A.
41.4
Protein Similarity:
100
99.6
51.7
83.3
N.A.
89
88.1
N.A.
63.7
49.6
51.5
76.5
N.A.
57.2
N.A.
N.A.
60.4
P-Site Identity:
100
100
0
40
N.A.
40
33.3
N.A.
20
0
13.3
26.6
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
26.6
40
N.A.
46.6
40
N.A.
20
26.6
13.3
33.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.7
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
22
15
0
22
0
15
15
0
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
22
% D
% Glu:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
22
0
0
0
0
0
0
15
0
8
% F
% Gly:
15
0
22
15
0
8
15
8
8
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
8
8
0
8
15
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
8
0
8
0
0
0
0
36
% K
% Leu:
15
36
15
8
8
8
8
0
0
0
22
58
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
22
36
15
0
8
0
0
36
0
22
8
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
22
36
8
0
29
0
22
15
8
8
50
15
% R
% Ser:
22
8
8
8
0
0
36
29
0
0
0
0
15
8
0
% S
% Thr:
8
0
8
0
8
22
8
15
22
22
0
0
8
0
0
% T
% Val:
0
22
8
0
0
15
8
8
15
22
22
0
0
15
8
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
36
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
15
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _