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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK5
All Species:
22.12
Human Site:
T166
Identified Species:
37.44
UniProt:
Q3MIX3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MIX3
NP_777582.3
580
65897
T166
L
P
P
E
Y
T
R
T
L
R
V
L
E
D
R
Chimpanzee
Pan troglodytes
XP_001157317
580
65781
T166
L
P
P
E
Y
T
R
T
L
R
V
L
E
D
R
Rhesus Macaque
Macaca mulatta
XP_001104139
523
59652
A160
P
L
G
T
A
S
L
A
Q
V
H
K
A
V
L
Dog
Lupus familis
XP_539216
624
71219
T210
L
P
P
E
Y
I
R
T
L
R
V
L
E
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80V03
582
66636
T166
L
P
T
E
Y
I
Q
T
L
R
V
L
E
D
K
Rat
Rattus norvegicus
NP_001129270
582
66734
T166
L
P
T
E
Y
I
Q
T
L
R
V
L
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507044
482
54419
I164
Y
W
W
C
S
N
V
I
L
R
G
L
D
E
N
Chicken
Gallus gallus
Q5ZMT7
519
59182
A157
P
L
G
A
A
S
L
A
Q
V
H
K
A
V
L
Frog
Xenopus laevis
Q6INL7
520
59525
T152
V
F
E
E
F
E
K
T
P
L
G
A
A
S
L
Zebra Danio
Brachydanio rerio
XP_001341554
579
66788
T166
L
P
P
E
Y
I
Q
T
L
H
V
L
E
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648446
557
64196
D155
C
L
P
T
T
Q
A
D
V
Q
K
V
F
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181542
582
67255
K201
L
P
K
E
I
L
Q
K
L
A
T
L
Q
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04212
538
60900
E159
M
P
D
Q
V
F
A
E
F
D
P
V
P
I
A
Baker's Yeast
Sacchar. cerevisiae
Q06567
569
65899
L168
D
E
L
F
K
E
D
L
G
T
S
I
E
D
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
34.4
77
N.A.
80.5
79.3
N.A.
56.2
32.2
32.9
60.5
N.A.
38.9
N.A.
N.A.
41.4
Protein Similarity:
100
99.6
51.7
83.3
N.A.
89
88.1
N.A.
63.7
49.6
51.5
76.5
N.A.
57.2
N.A.
N.A.
60.4
P-Site Identity:
100
100
0
93.3
N.A.
73.3
73.3
N.A.
20
0
13.3
73.3
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
33.3
6.6
33.3
86.6
N.A.
33.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.7
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
15
0
15
15
0
8
0
8
22
0
8
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
8
8
0
8
0
0
8
58
0
% D
% Glu:
0
8
8
58
0
15
0
8
0
0
0
0
50
8
0
% E
% Phe:
0
8
0
8
8
8
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
8
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
15
0
0
0
0
% H
% Ile:
0
0
0
0
8
29
0
8
0
0
0
8
0
8
0
% I
% Lys:
0
0
8
0
8
0
8
8
0
0
8
15
0
0
29
% K
% Leu:
50
22
8
0
0
8
15
8
58
8
0
58
0
0
22
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
15
58
36
0
0
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
0
0
8
0
8
29
0
15
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
22
0
0
43
0
0
0
8
29
% R
% Ser:
0
0
0
0
8
15
0
0
0
0
8
0
0
8
0
% S
% Thr:
0
0
15
15
8
15
0
50
0
8
8
0
0
0
0
% T
% Val:
8
0
0
0
8
0
8
0
8
15
43
15
0
15
0
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
43
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _