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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK5 All Species: 12.05
Human Site: Y575 Identified Species: 20.39
UniProt: Q3MIX3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MIX3 NP_777582.3 580 65897 Y575 V P P A E E L Y Q Y L E T _ _
Chimpanzee Pan troglodytes XP_001157317 580 65781 Y575 V P P A E E L Y Q Y L E T _ _
Rhesus Macaque Macaca mulatta XP_001104139 523 59652 L512 L K L A D R V L A L I C W L F
Dog Lupus familis XP_539216 624 71219 S619 L P E T Q G L S E F L E T _ _
Cat Felis silvestris
Mouse Mus musculus Q80V03 582 66636 E575 A P K A E A E E V Y Q Y L E M
Rat Rattus norvegicus NP_001129270 582 66734 E575 A P K A E A E E V Y Q Y L E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507044 482 54419 Y477 I A Q P E G L Y E Y L E T _ _
Chicken Gallus gallus Q5ZMT7 519 59182 S502 L F L W L K G S R L G S W V I
Frog Xenopus laevis Q6INL7 520 59525 G507 L R L Q S C I G R W I N H V L
Zebra Danio Brachydanio rerio XP_001341554 579 66788
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648446 557 64196 M548 R T V M K D I M Q P P E P N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181542 582 67255 L572 V G D I F S S L V P P R A S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04212 538 60900
Baker's Yeast Sacchar. cerevisiae Q06567 569 65899 P563 L W W K K F I P K T W L S S _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 34.4 77 N.A. 80.5 79.3 N.A. 56.2 32.2 32.9 60.5 N.A. 38.9 N.A. N.A. 41.4
Protein Similarity: 100 99.6 51.7 83.3 N.A. 89 88.1 N.A. 63.7 49.6 51.5 76.5 N.A. 57.2 N.A. N.A. 60.4
P-Site Identity: 100 100 6.6 38.4 N.A. 26.6 26.6 N.A. 53.8 0 0 0 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 33.3 69.2 N.A. 26.6 26.6 N.A. 69.2 26.6 33.3 0 N.A. 33.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 51.7 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 35.7 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 36 0 15 0 0 8 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 8 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 36 15 15 15 15 0 0 36 0 15 0 % E
% Phe: 0 8 0 0 8 8 0 0 0 8 0 0 0 0 8 % F
% Gly: 0 8 0 0 0 15 8 8 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 8 0 0 22 0 0 0 15 0 0 0 8 % I
% Lys: 0 8 15 8 15 8 0 0 8 0 0 0 0 0 0 % K
% Leu: 36 0 22 0 8 0 29 15 0 15 29 8 15 8 8 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 36 15 8 0 0 0 8 0 15 15 0 8 0 8 % P
% Gln: 0 0 8 8 8 0 0 0 22 0 15 0 0 0 0 % Q
% Arg: 8 8 0 0 0 8 0 0 15 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 8 8 8 15 0 0 0 8 8 15 0 % S
% Thr: 0 8 0 8 0 0 0 0 0 8 0 0 29 0 0 % T
% Val: 22 0 8 0 0 0 8 0 22 0 0 0 0 15 8 % V
% Trp: 0 8 8 8 0 0 0 0 0 8 8 0 15 0 0 % W
% Tyr: 0 0 0 0 0 0 0 22 0 36 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 29 36 % _