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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR72 All Species: 8.79
Human Site: S518 Identified Species: 19.33
UniProt: Q3MJ13 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3MJ13 NP_877435.2 1102 123425 S518 P V T S L L M S P E K F K L R
Chimpanzee Pan troglodytes XP_510422 1102 123321 S518 P V T S L L M S P E K F K L R
Rhesus Macaque Macaca mulatta XP_001088410 1102 123300 S518 A V T S L L M S P E K F K L R
Dog Lupus familis XP_544687 1130 126491 F546 I L M S P E N F R L R S D Q V
Cat Felis silvestris
Mouse Mus musculus Q920I9 1489 163386 V520 G E I T Q L L V P P E N C S A
Rat Rattus norvegicus Q9ERH3 1488 163172 V520 G E I T Q L L V P P E N C S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509971 1087 122224 V513 E H G I V C C V C G D H S V A
Chicken Gallus gallus XP_425069 927 103611 L392 A E G I I D H L C D S K D G I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569960 1525 168458 P518 E I T Q L L V P P E S C S P R
Honey Bee Apis mellifera XP_395749 1488 164925 P522 E I T Q L M V P P D N C S P R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784047 1449 158495 P526 E L T R I V I P P A S C N A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96 82.4 N.A. 28.4 28 N.A. 57.4 53.9 N.A. N.A. N.A. 24.6 24.3 N.A. 26.8
Protein Similarity: 100 99.5 97.8 89.5 N.A. 46 45.6 N.A. 70.5 65.7 N.A. N.A. N.A. 41.2 41.9 N.A. 43.8
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 13.3 N.A. 0 0 N.A. N.A. N.A. 40 26.6 N.A. 20
P-Site Similarity: 100 100 93.3 20 N.A. 33.3 33.3 N.A. 13.3 13.3 N.A. N.A. N.A. 53.3 53.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 0 0 0 10 0 0 0 10 28 % A
% Cys: 0 0 0 0 0 10 10 0 19 0 0 28 19 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 19 10 0 19 0 0 % D
% Glu: 37 28 0 0 0 10 0 0 0 37 19 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 28 0 0 0 % F
% Gly: 19 0 19 0 0 0 0 0 0 10 0 0 0 10 0 % G
% His: 0 10 0 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 10 19 19 19 19 0 10 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 28 10 28 0 0 % K
% Leu: 0 19 0 0 46 55 19 10 0 10 0 0 0 28 0 % L
% Met: 0 0 10 0 0 10 28 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 10 19 10 0 0 % N
% Pro: 19 0 0 0 10 0 0 28 73 19 0 0 0 19 0 % P
% Gln: 0 0 0 19 19 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 10 0 0 0 0 10 0 10 0 0 0 55 % R
% Ser: 0 0 0 37 0 0 0 28 0 0 28 10 28 19 0 % S
% Thr: 0 0 55 19 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 28 0 0 10 10 19 28 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _