KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR72
All Species:
8.79
Human Site:
S749
Identified Species:
19.33
UniProt:
Q3MJ13
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MJ13
NP_877435.2
1102
123425
S749
L
A
K
P
I
T
E
S
L
A
Q
G
D
N
T
Chimpanzee
Pan troglodytes
XP_510422
1102
123321
S749
L
A
K
P
I
T
E
S
L
A
Q
G
D
N
T
Rhesus Macaque
Macaca mulatta
XP_001088410
1102
123300
S749
Q
A
K
P
I
T
E
S
L
S
Q
G
D
N
T
Dog
Lupus familis
XP_544687
1130
126491
N775
Q
A
K
P
V
V
E
N
P
A
Q
G
D
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q920I9
1489
163386
I754
K
E
T
I
K
E
N
I
K
E
H
L
L
D
E
Rat
Rattus norvegicus
Q9ERH3
1488
163172
I754
K
E
T
I
K
E
N
I
K
E
H
L
L
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509971
1087
122224
H730
G
R
T
G
C
G
G
H
G
P
R
E
D
L
P
Chicken
Gallus gallus
XP_425069
927
103611
E594
L
E
R
H
E
T
G
E
I
A
K
A
I
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569960
1525
168458
K789
K
T
E
I
V
E
K
K
V
Q
A
K
V
E
S
Honey Bee
Apis mellifera
XP_395749
1488
164925
K762
F
F
G
R
V
K
D
K
A
G
D
V
E
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784047
1449
158495
Q758
I
S
E
Q
I
K
K
Q
I
G
D
S
D
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96
82.4
N.A.
28.4
28
N.A.
57.4
53.9
N.A.
N.A.
N.A.
24.6
24.3
N.A.
26.8
Protein Similarity:
100
99.5
97.8
89.5
N.A.
46
45.6
N.A.
70.5
65.7
N.A.
N.A.
N.A.
41.2
41.9
N.A.
43.8
P-Site Identity:
100
100
86.6
66.6
N.A.
0
0
N.A.
6.6
20
N.A.
N.A.
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
6.6
6.6
N.A.
13.3
46.6
N.A.
N.A.
N.A.
33.3
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
10
37
10
10
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
19
0
55
19
10
% D
% Glu:
0
28
19
0
10
28
37
10
0
19
0
10
10
10
19
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
10
0
10
19
0
10
19
0
37
0
0
0
% G
% His:
0
0
0
10
0
0
0
10
0
0
19
0
0
0
0
% H
% Ile:
10
0
0
28
37
0
0
19
19
0
0
0
10
0
10
% I
% Lys:
28
0
37
0
19
19
19
19
19
0
10
10
0
0
0
% K
% Leu:
28
0
0
0
0
0
0
0
28
0
0
19
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
10
0
0
0
0
0
37
0
% N
% Pro:
0
0
0
37
0
0
0
0
10
10
0
0
0
0
10
% P
% Gln:
19
0
0
10
0
0
0
10
0
10
37
0
0
0
0
% Q
% Arg:
0
10
10
10
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
0
28
0
10
0
10
0
10
19
% S
% Thr:
0
10
28
0
0
37
0
0
0
0
0
0
0
0
37
% T
% Val:
0
0
0
0
28
10
0
0
10
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _