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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLA2G4E
All Species:
8.79
Human Site:
S474
Identified Species:
27.62
UniProt:
Q3MJ16
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3MJ16
NP_001073959
838
95687
S474
S
D
Q
R
A
A
L
S
C
G
Q
N
P
L
P
Chimpanzee
Pan troglodytes
XP_523058
860
98041
S496
S
D
Q
R
A
A
L
S
C
G
Q
N
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001102436
817
91391
R453
G
Q
R
A
A
L
E
R
G
Q
N
P
L
P
L
Dog
Lupus familis
XP_544638
800
91612
S436
S
D
Q
R
A
A
L
S
Q
G
Q
N
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q50L42
875
100138
C512
S
D
Q
R
A
A
L
C
R
G
Q
N
P
L
P
Rat
Rattus norvegicus
XP_230487
915
104975
C552
S
E
Q
R
A
A
L
C
R
G
Q
N
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516356
384
44300
E41
N
Q
D
F
R
V
W
E
D
V
L
E
E
V
S
Chicken
Gallus gallus
XP_421151
836
96009
D479
S
D
Q
Q
R
A
I
D
R
G
Q
N
P
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
43.4
81.3
N.A.
73.3
71.6
N.A.
35.2
52.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.6
62.8
87.3
N.A.
82.8
80.2
N.A.
40.8
69.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
80
N.A.
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
86.6
N.A.
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
75
75
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
25
25
0
0
0
0
0
0
% C
% Asp:
0
63
13
0
0
0
0
13
13
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
13
13
0
0
0
13
13
0
0
% E
% Phe:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
13
75
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
13
63
0
0
0
13
0
13
75
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
75
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
75
13
75
% P
% Gln:
0
25
75
13
0
0
0
0
13
13
75
0
0
0
0
% Q
% Arg:
0
0
13
63
25
0
0
13
38
0
0
0
0
0
0
% R
% Ser:
75
0
0
0
0
0
0
38
0
0
0
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
13
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _