KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL1
All Species:
16.06
Human Site:
S166
Identified Species:
27.18
UniProt:
Q3SXM5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SXM5
NP_001139523.1
330
37018
S166
P
Q
Y
F
T
Q
L
S
E
D
K
L
W
D
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112266
330
36970
S166
P
Q
Y
F
T
Q
L
S
E
D
K
L
W
D
I
Dog
Lupus familis
XP_536765
330
37069
S166
P
Q
Y
F
T
Q
V
S
E
D
K
L
W
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTX9
330
36849
P166
P
Q
Y
F
S
Q
V
P
E
D
T
L
W
D
I
Rat
Rattus norvegicus
Q4V8B7
330
36889
P166
P
Q
Y
F
S
Q
V
P
E
D
T
I
W
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509376
330
37373
P166
P
Q
Y
F
T
Q
V
P
E
D
K
L
W
D
I
Chicken
Gallus gallus
Q5ZJG8
331
37589
S166
P
D
Y
F
T
N
L
S
E
D
M
L
W
D
M
Frog
Xenopus laevis
Q5XG41
318
34975
T158
E
I
P
D
L
E
N
T
L
D
K
M
I
N
I
Zebra Danio
Brachydanio rerio
A5WWC6
319
35106
I158
S
F
D
G
T
L
E
I
S
Q
N
F
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724023
324
36393
L158
D
K
V
S
E
D
M
L
W
D
L
L
T
V
N
Honey Bee
Apis mellifera
XP_393710
291
32768
I135
D
L
W
D
I
I
N
I
N
I
G
A
T
T
L
Nematode Worm
Caenorhab. elegans
Q09517
316
34290
T159
E
R
L
A
N
I
T
T
I
N
T
L
P
P
T
Sea Urchin
Strong. purpuratus
XP_788968
356
39637
D166
P
Q
L
F
L
E
M
D
A
D
R
I
R
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYE5
332
36765
D157
P
V
P
F
L
Q
T
D
R
D
E
L
Q
N
I
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.7
N.A.
87.5
86.6
N.A.
86
64.9
43.9
52.1
N.A.
38.7
42.7
35.1
47.7
Protein Similarity:
100
N.A.
99.6
98.1
N.A.
93.9
93.6
N.A.
92.4
80.6
61.5
67.8
N.A.
59.3
57.5
53.9
64.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
66.6
N.A.
86.6
73.3
20
6.6
N.A.
13.3
0
6.6
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
93.3
80
46.6
20
N.A.
26.6
13.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
8
15
0
8
0
15
0
79
0
0
0
50
0
% D
% Glu:
15
0
0
0
8
15
8
0
50
0
8
0
0
8
0
% E
% Phe:
0
8
0
65
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
15
0
15
8
8
0
15
8
0
58
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
36
0
0
0
0
% K
% Leu:
0
8
15
0
22
8
22
8
8
0
8
65
8
0
22
% L
% Met:
0
0
0
0
0
0
15
0
0
0
8
8
0
0
8
% M
% Asn:
0
0
0
0
8
8
15
0
8
8
8
0
0
15
8
% N
% Pro:
65
0
15
0
0
0
0
22
0
0
0
0
8
8
0
% P
% Gln:
0
50
0
0
0
50
0
0
0
8
0
0
8
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
8
0
8
0
0
% R
% Ser:
8
0
0
8
15
0
0
29
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
43
0
15
15
0
0
22
0
15
8
8
% T
% Val:
0
8
8
0
0
0
29
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
50
0
0
% W
% Tyr:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _