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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL1
All Species:
33.64
Human Site:
Y21
Identified Species:
56.92
UniProt:
Q3SXM5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SXM5
NP_001139523.1
330
37018
Y21
I
A
R
S
C
N
C
Y
M
E
A
L
A
L
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112266
330
36970
Y21
I
A
R
S
C
N
C
Y
M
E
A
L
A
L
V
Dog
Lupus familis
XP_536765
330
37069
Y21
I
A
R
S
C
N
C
Y
M
E
A
L
A
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTX9
330
36849
Y21
I
A
R
S
C
N
C
Y
M
E
A
L
A
L
V
Rat
Rattus norvegicus
Q4V8B7
330
36889
Y21
I
A
R
S
C
S
C
Y
V
E
A
L
A
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509376
330
37373
Y21
I
A
R
S
C
N
C
Y
L
E
A
L
A
L
V
Chicken
Gallus gallus
Q5ZJG8
331
37589
Y21
I
S
R
S
C
S
V
Y
I
E
A
L
A
I
V
Frog
Xenopus laevis
Q5XG41
318
34975
L21
C
F
W
Y
L
G
V
L
A
A
A
W
W
G
L
Zebra Danio
Brachydanio rerio
A5WWC6
319
35106
Y21
I
A
R
S
C
S
G
Y
V
E
T
L
A
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724023
324
36393
V21
I
V
G
S
L
S
I
V
A
Y
L
Y
E
N
L
Honey Bee
Apis mellifera
XP_393710
291
32768
Nematode Worm
Caenorhab. elegans
Q09517
316
34290
L23
A
A
V
A
Y
R
L
L
T
I
F
S
N
I
L
Sea Urchin
Strong. purpuratus
XP_788968
356
39637
Y22
V
S
N
G
F
H
I
Y
S
E
V
L
S
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYE5
332
36765
G21
Y
G
Q
W
A
L
A
G
I
G
A
L
Y
V
A
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.7
N.A.
87.5
86.6
N.A.
86
64.9
43.9
52.1
N.A.
38.7
42.7
35.1
47.7
Protein Similarity:
100
N.A.
99.6
98.1
N.A.
93.9
93.6
N.A.
92.4
80.6
61.5
67.8
N.A.
59.3
57.5
53.9
64.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
86.6
N.A.
93.3
66.6
6.6
73.3
N.A.
13.3
0
6.6
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
13.3
86.6
N.A.
26.6
0
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
0
8
8
0
8
0
15
8
65
0
58
0
8
% A
% Cys:
8
0
0
0
58
0
43
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
65
0
0
8
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
8
8
0
8
8
8
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
65
0
0
0
0
0
15
0
15
8
0
0
0
15
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
15
8
8
15
8
0
8
72
0
58
22
% L
% Met:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
36
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
58
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
65
0
29
0
0
8
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% T
% Val:
8
8
8
0
0
0
15
8
15
0
8
0
0
8
58
% V
% Trp:
0
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
8
0
0
8
8
0
0
65
0
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _