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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL1
All Species:
34.24
Human Site:
Y236
Identified Species:
57.95
UniProt:
Q3SXM5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SXM5
NP_001139523.1
330
37018
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112266
330
36970
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Dog
Lupus familis
XP_536765
330
37069
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTX9
330
36849
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Rat
Rattus norvegicus
Q4V8B7
330
36889
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509376
330
37373
Y236
S
R
A
L
Q
Y
E
Y
A
S
K
G
I
F
V
Chicken
Gallus gallus
Q5ZJG8
331
37589
Y236
S
R
A
L
Y
Y
E
Y
A
S
K
G
I
F
V
Frog
Xenopus laevis
Q5XG41
318
34975
Y225
S
R
G
L
H
A
E
Y
R
N
K
G
I
N
V
Zebra Danio
Brachydanio rerio
A5WWC6
319
35106
T222
K
A
A
F
S
A
S
T
A
F
L
D
N
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724023
324
36393
V224
T
K
G
L
E
Y
E
V
A
E
H
N
I
H
V
Honey Bee
Apis mellifera
XP_393710
291
32768
G199
R
A
E
Y
S
K
F
G
L
T
I
Q
H
L
S
Nematode Worm
Caenorhab. elegans
Q09517
316
34290
Q223
L
R
K
E
Y
E
H
Q
G
I
T
V
Q
T
I
Sea Urchin
Strong. purpuratus
XP_788968
356
39637
Y236
S
Q
A
L
E
Y
E
Y
K
D
Y
G
I
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYE5
332
36765
L227
S
S
A
L
S
A
E
L
K
D
Q
G
V
D
V
Conservation
Percent
Protein Identity:
100
N.A.
98.4
92.7
N.A.
87.5
86.6
N.A.
86
64.9
43.9
52.1
N.A.
38.7
42.7
35.1
47.7
Protein Similarity:
100
N.A.
99.6
98.1
N.A.
93.9
93.6
N.A.
92.4
80.6
61.5
67.8
N.A.
59.3
57.5
53.9
64.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
60
20
N.A.
40
0
6.6
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
66.6
20
N.A.
60
6.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
72
0
0
22
0
0
65
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
0
8
0
8
0
% D
% Glu:
0
0
8
8
15
8
79
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
8
0
0
0
58
0
% F
% Gly:
0
0
15
0
0
0
0
8
8
0
0
72
0
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
8
0
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
72
8
8
% I
% Lys:
8
8
8
0
0
8
0
0
15
0
58
0
0
0
0
% K
% Leu:
8
0
0
79
0
0
0
8
8
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
43
0
0
8
0
0
8
8
8
0
0
% Q
% Arg:
8
65
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
72
8
0
0
22
0
8
0
0
50
0
0
0
0
15
% S
% Thr:
8
0
0
0
0
0
0
8
0
8
8
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
79
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
15
65
0
65
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _