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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
29.7
Human Site:
S365
Identified Species:
46.67
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
S365
N
V
P
I
I
E
D
S
T
D
F
F
K
S
G
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
S365
N
V
P
I
I
E
D
S
T
D
F
F
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
S365
N
V
P
I
I
E
D
S
T
D
F
F
K
S
G
Dog
Lupus familis
XP_531763
923
101579
S365
N
V
P
V
I
E
D
S
T
D
F
F
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
S365
N
T
P
V
I
E
D
S
T
D
F
F
K
S
G
Rat
Rattus norvegicus
P28037
902
99108
S344
N
V
P
E
V
E
D
S
T
D
F
F
K
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
A452
N
V
P
A
I
E
G
A
T
D
F
F
K
S
G
Chicken
Gallus gallus
O93344
518
56713
L33
L
P
S
P
T
L
N
L
E
I
K
H
T
K
I
Frog
Xenopus laevis
Q6GNL7
902
99964
S344
N
V
S
E
I
E
D
S
T
D
F
F
K
A
G
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
T365
N
V
A
A
I
E
E
T
T
D
F
F
K
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
D346
M
D
V
N
E
D
T
D
F
F
A
C
G
A
G
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
D354
T
Q
V
S
S
D
T
D
F
F
E
S
G
A
S
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
D344
S
T
P
D
I
S
G
D
T
D
F
F
K
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
V53
E
E
I
I
N
P
S
V
Q
V
S
H
T
Q
L
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
P35
L
R
V
P
I
T
L
P
N
G
F
T
Y
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
0
80
66.6
N.A.
N.A.
6.6
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
6.6
86.6
80
N.A.
N.A.
20
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
14
0
0
0
7
0
0
7
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% C
% Asp:
0
7
0
7
0
14
47
20
0
67
0
0
0
0
0
% D
% Glu:
7
7
0
14
7
60
7
0
7
0
7
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
14
14
74
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
14
0
0
7
0
0
14
0
74
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
0
7
27
67
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
0
67
7
0
% K
% Leu:
14
0
0
0
0
7
7
7
0
0
0
0
0
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
60
0
0
7
7
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
0
7
54
14
0
7
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
7
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
14
7
7
7
7
47
0
0
7
7
0
47
7
% S
% Thr:
7
14
0
0
7
7
14
7
67
0
0
7
14
0
0
% T
% Val:
0
54
20
14
7
0
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _