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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
38.18
Human Site:
S375
Identified Species:
60
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
S375
F
F
K
S
G
A
S
S
M
D
V
A
R
L
V
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
S375
F
F
K
S
G
A
S
S
M
D
V
A
R
L
V
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
S375
F
F
K
S
G
A
S
S
M
D
V
A
R
L
V
Dog
Lupus familis
XP_531763
923
101579
S375
F
F
K
S
G
A
S
S
M
D
V
V
R
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
S375
F
F
K
S
G
A
S
S
M
D
V
V
R
L
V
Rat
Rattus norvegicus
P28037
902
99108
S354
F
F
K
S
G
A
A
S
V
D
V
V
R
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
S462
F
F
K
S
G
A
S
S
M
D
V
V
R
M
V
Chicken
Gallus gallus
O93344
518
56713
N43
K
H
T
K
I
F
I
N
N
E
W
Q
N
S
E
Frog
Xenopus laevis
Q6GNL7
902
99964
S354
F
F
K
A
G
A
A
S
M
D
V
V
R
L
V
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
S375
F
F
K
C
G
A
A
S
M
D
V
V
R
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
D356
A
C
G
A
G
S
M
D
V
I
R
L
V
E
E
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
D364
E
S
G
A
S
S
A
D
V
T
R
L
V
E
E
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
S354
F
F
K
M
G
A
G
S
M
D
V
A
R
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
N63
S
H
T
Q
L
L
I
N
G
N
F
V
D
S
A
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
G45
F
T
Y
E
Q
P
T
G
L
F
I
N
G
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
80
N.A.
86.6
0
80
80
N.A.
N.A.
6.6
0
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
13.3
93.3
86.6
N.A.
N.A.
26.6
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
20
0
67
27
0
0
0
0
27
0
0
7
% A
% Cys:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
14
0
67
0
0
7
0
0
% D
% Glu:
7
0
0
7
0
0
0
0
0
7
0
0
0
20
20
% E
% Phe:
74
67
0
0
0
7
0
0
0
7
7
0
0
0
7
% F
% Gly:
0
0
14
0
74
0
7
7
7
0
0
0
7
0
0
% G
% His:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
14
0
0
7
7
0
0
0
0
% I
% Lys:
7
0
67
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
7
0
0
7
0
0
14
0
60
0
% L
% Met:
0
0
0
7
0
0
7
0
60
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
14
7
7
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
14
0
67
0
0
% R
% Ser:
7
7
0
47
7
14
40
67
0
0
0
0
0
14
0
% S
% Thr:
0
7
14
0
0
0
7
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
20
0
67
47
14
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _