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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1L2 All Species: 49.09
Human Site: S692 Identified Species: 77.14
UniProt: Q3SY69 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3SY69 NP_001029345.2 923 101746 S692 V S N L K K V S L E L G G K S
Chimpanzee Pan troglodytes XP_001160213 923 101833 S692 V S N L K K V S L E L G G K S
Rhesus Macaque Macaca mulatta XP_001089566 923 101792 S692 V S N L K K V S L E L G G K S
Dog Lupus familis XP_531763 923 101579 S692 V S N L K K V S L E L G G K S
Cat Felis silvestris
Mouse Mus musculus Q8K009 923 101546 S692 V S N L K K V S L E L G G K S
Rat Rattus norvegicus P28037 902 99108 S671 L S N V K K V S L E L G G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505782 1010 111425 S779 V S N L K K V S L E L G G K S
Chicken Gallus gallus O93344 518 56713 C319 V F F N Q G Q C C T A G S R I
Frog Xenopus laevis Q6GNL7 902 99964 S671 V S N V K K V S L E L G G K S
Zebra Danio Brachydanio rerio XP_002661418 923 101483 S692 V S N L K K V S L E L G G K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623798 900 99997 S669 N S N L K K V S L E L G G K S
Nematode Worm Caenorhab. elegans NP_502054 908 99259 S677 K S N I K K V S L E L G G K S
Sea Urchin Strong. purpuratus XP_784777 884 96767 S669 E S N L K K V S L E L G G K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570 C339 F F N Q G Q C C C A G S R T F
Baker's Yeast Sacchar. cerevisiae P40047 520 56602 V321 I F Y N S G E V C C A G S R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 96 N.A. 92.1 71.9 N.A. 82.8 29.4 75.5 80.5 N.A. N.A. 61 58.6 69.4
Protein Similarity: 100 99.7 99.4 97.9 N.A. 96.7 85.8 N.A. 87.8 40.7 88 93 N.A. N.A. 76.3 74.4 81.6
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. 100 13.3 93.3 100 N.A. N.A. 93.3 86.6 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 100 100 N.A. N.A. 93.3 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 28.6 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. 39.8 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 14 20 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 7 0 0 80 0 0 0 0 0 % E
% Phe: 7 20 7 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 7 14 0 0 0 0 7 94 80 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 14 % I
% Lys: 7 0 0 0 80 80 0 0 0 0 0 0 0 80 0 % K
% Leu: 7 0 0 60 0 0 0 0 80 0 80 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 87 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 7 7 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 0 % R
% Ser: 0 80 0 0 7 0 0 80 0 0 0 7 14 0 80 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % T
% Val: 60 0 0 14 0 0 80 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _