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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
30.61
Human Site:
T332
Identified Species:
48.1
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
T332
Q
Y
F
S
T
G
E
T
S
V
V
E
L
T
A
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
T332
Q
Y
F
S
T
G
E
T
S
V
V
E
L
T
A
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
T332
Q
Y
F
S
A
G
E
T
S
V
V
E
L
T
A
Dog
Lupus familis
XP_531763
923
101579
T332
Q
Y
F
S
A
G
E
T
S
V
V
E
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
T332
Q
Y
F
S
A
G
E
T
S
V
V
E
L
T
A
Rat
Rattus norvegicus
P28037
902
99108
S311
Q
F
F
K
G
S
A
S
S
D
L
E
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
T419
K
Y
F
S
A
G
E
T
S
A
V
E
L
T
E
Chicken
Gallus gallus
O93344
518
56713
Frog
Xenopus laevis
Q6GNL7
902
99964
S311
Q
Y
F
K
T
A
D
S
A
A
L
Q
L
S
E
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
S332
K
Y
F
S
S
E
E
S
A
S
L
D
L
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
D313
K
F
G
Q
K
S
E
D
T
I
I
E
F
T
A
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
V321
Y
G
Q
G
A
D
Q
V
Q
E
L
V
L
T
D
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
A311
K
Y
G
Q
S
M
D
A
E
E
K
L
E
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
L20
S
F
S
A
S
S
P
L
L
F
R
S
Q
G
R
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
40
N.A.
73.3
0
33.3
40
N.A.
N.A.
26.6
13.3
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
60
N.A.
80
0
73.3
80
N.A.
N.A.
60
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
34
7
7
7
14
14
0
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
14
7
0
7
0
7
0
0
14
% D
% Glu:
0
0
0
0
0
7
54
0
7
14
0
54
7
0
20
% E
% Phe:
0
20
60
0
0
0
0
0
0
7
0
0
7
0
0
% F
% Gly:
0
7
14
7
7
40
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% I
% Lys:
27
0
0
14
7
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
7
7
0
27
7
67
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
47
0
7
14
0
0
7
0
7
0
0
7
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% R
% Ser:
7
0
7
47
20
20
0
20
47
7
0
7
0
7
0
% S
% Thr:
0
0
0
0
20
0
0
40
7
0
0
0
0
67
7
% T
% Val:
0
0
0
0
0
0
0
7
0
34
40
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _