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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
39.39
Human Site:
T459
Identified Species:
61.9
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
T459
T
D
A
D
D
G
K
T
Y
D
T
I
N
P
T
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
T459
T
D
A
D
D
G
K
T
Y
D
T
I
N
P
T
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
T459
T
D
A
D
D
G
K
T
Y
D
T
I
N
P
T
Dog
Lupus familis
XP_531763
923
101579
T459
T
D
A
N
D
G
K
T
Y
D
T
I
N
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
T459
V
D
A
E
D
G
E
T
Y
A
T
V
N
P
T
Rat
Rattus norvegicus
P28037
902
99108
T438
V
D
A
E
G
S
K
T
Y
N
T
I
N
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
T546
V
D
A
E
E
A
K
T
Y
D
T
I
N
P
T
Chicken
Gallus gallus
O93344
518
56713
L106
A
S
E
R
G
Q
L
L
D
K
L
A
D
L
V
Frog
Xenopus laevis
Q6GNL7
902
99964
S438
M
D
A
E
G
G
K
S
Y
D
T
I
N
P
T
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
T459
E
D
A
D
D
G
K
T
Y
N
T
V
N
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
P436
F
V
N
G
H
G
N
P
I
D
T
I
N
P
H
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
T444
V
G
S
S
D
G
R
T
F
K
T
I
N
P
A
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
T436
M
D
S
E
S
G
N
T
F
K
T
I
N
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
L126
Y
E
R
S
R
V
L
L
R
F
A
D
L
V
E
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
K108
V
E
P
E
V
R
A
K
A
L
F
N
L
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
73.3
0
73.3
80
N.A.
N.A.
40
46.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
86.6
6.6
86.6
93.3
N.A.
N.A.
40
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
60
0
0
7
7
0
7
7
7
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
27
47
0
0
0
7
47
0
7
7
0
7
% D
% Glu:
7
14
7
40
7
0
7
0
0
0
0
0
0
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
14
7
7
0
0
0
0
% F
% Gly:
0
7
0
7
20
67
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
14
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
67
0
0
0
% I
% Lys:
0
0
0
0
0
0
54
7
0
20
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
14
14
0
7
7
0
14
7
0
% L
% Met:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
14
0
0
14
0
7
80
0
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
0
0
0
0
80
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
7
7
7
0
7
0
0
0
0
0
0
% R
% Ser:
0
7
14
14
7
7
0
7
0
0
0
0
0
0
0
% S
% Thr:
27
0
0
0
0
0
0
67
0
0
80
0
0
0
60
% T
% Val:
34
7
0
0
7
7
0
0
0
0
0
14
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _