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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
24.24
Human Site:
Y18
Identified Species:
38.1
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
Y18
R
F
S
T
G
R
V
Y
F
K
N
K
L
K
L
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
Y18
R
F
S
T
G
R
V
Y
F
K
N
K
L
K
L
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
Y18
R
F
S
T
G
R
V
Y
F
K
N
K
L
K
L
Dog
Lupus familis
XP_531763
923
101579
Y18
R
F
S
T
G
Q
A
Y
F
K
N
K
L
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
Y18
H
F
S
T
S
R
V
Y
F
K
N
K
L
K
L
Rat
Rattus norvegicus
P28037
902
99108
R20
Q
E
V
Y
C
Q
L
R
K
E
G
H
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
Y105
N
T
A
L
L
M
V
Y
Y
Q
N
K
L
K
L
Chicken
Gallus gallus
O93344
518
56713
Frog
Xenopus laevis
Q6GNL7
902
99964
L19
G
R
E
V
Y
R
E
L
L
K
E
G
H
Q
V
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
Y18
K
F
S
S
S
S
V
Y
Y
Q
N
K
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
V18
Q
S
N
F
A
A
E
V
Y
K
L
L
K
L
N
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
L19
G
V
D
V
Y
K
E
L
R
K
N
G
H
E
I
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
L19
G
E
E
V
Y
K
L
L
R
K
D
G
H
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
46.6
0
13.3
60
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
33.3
N.A.
66.6
0
26.6
86.6
N.A.
N.A.
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
14
14
0
0
0
20
0
0
7
7
0
7
14
0
% E
% Phe:
0
40
0
7
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
20
0
0
0
27
0
0
0
0
0
7
20
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
7
20
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% I
% Lys:
7
0
0
0
0
14
0
0
7
60
0
47
7
47
0
% K
% Leu:
0
0
0
7
7
0
14
20
7
0
7
7
47
7
47
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
0
0
0
54
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
14
0
0
0
14
0
0
0
7
0
% Q
% Arg:
27
7
0
0
0
34
0
7
14
0
0
0
0
0
0
% R
% Ser:
0
7
40
7
14
7
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
7
0
34
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
7
20
0
0
40
7
0
0
0
0
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
20
0
0
47
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _