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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1L2
All Species:
4.55
Human Site:
Y818
Identified Species:
7.14
UniProt:
Q3SY69
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY69
NP_001029345.2
923
101746
Y818
V
F
T
D
V
E
D
Y
M
Y
L
A
K
E
E
Chimpanzee
Pan troglodytes
XP_001160213
923
101833
Y818
V
F
T
D
V
E
D
Y
M
Y
L
A
K
E
E
Rhesus Macaque
Macaca mulatta
XP_001089566
923
101792
H818
V
F
T
D
V
E
D
H
M
Y
L
A
K
E
E
Dog
Lupus familis
XP_531763
923
101579
H818
V
F
T
D
V
E
D
H
M
Y
L
A
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K009
923
101546
H818
V
F
T
G
V
E
D
H
M
Y
L
A
K
E
E
Rat
Rattus norvegicus
P28037
902
99108
H797
V
F
T
D
V
E
D
H
M
Y
I
A
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505782
1010
111425
H905
V
F
T
D
V
E
D
H
M
Y
L
A
R
E
E
Chicken
Gallus gallus
O93344
518
56713
K415
T
D
D
M
R
I
A
K
E
E
I
F
G
P
V
Frog
Xenopus laevis
Q6GNL7
902
99964
E797
I
F
T
D
V
T
D
E
M
F
I
A
K
E
E
Zebra Danio
Brachydanio rerio
XP_002661418
923
101483
H818
V
F
T
D
V
E
D
H
M
F
I
A
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623798
900
99997
D795
I
F
T
D
V
K
D
D
M
Y
I
A
K
E
E
Nematode Worm
Caenorhab. elegans
NP_502054
908
99259
E803
I
L
S
N
I
D
D
E
N
F
A
A
S
E
E
Sea Urchin
Strong. purpuratus
XP_784777
884
96767
V771
V
K
E
G
A
T
L
V
H
G
G
K
Q
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
D435
D
D
M
L
I
A
Q
D
E
I
F
G
P
V
Q
Baker's Yeast
Sacchar. cerevisiae
P40047
520
56602
K417
K
G
D
M
R
I
V
K
E
E
V
F
G
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96
N.A.
92.1
71.9
N.A.
82.8
29.4
75.5
80.5
N.A.
N.A.
61
58.6
69.4
Protein Similarity:
100
99.7
99.4
97.9
N.A.
96.7
85.8
N.A.
87.8
40.7
88
93
N.A.
N.A.
76.3
74.4
81.6
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
0
66.6
80
N.A.
N.A.
73.3
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
6.6
86.6
100
N.A.
N.A.
93.3
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
7
0
0
0
7
74
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
14
60
0
7
74
14
0
0
0
0
0
0
7
% D
% Glu:
0
0
7
0
0
54
0
14
20
14
0
0
0
74
74
% E
% Phe:
0
67
0
0
0
0
0
0
0
20
7
14
0
0
0
% F
% Gly:
0
7
0
14
0
0
0
0
0
7
7
7
14
0
0
% G
% His:
0
0
0
0
0
0
0
40
7
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
14
14
0
0
0
7
34
0
0
0
7
% I
% Lys:
7
7
0
0
0
7
0
14
0
0
0
7
60
0
0
% K
% Leu:
0
7
0
7
0
0
7
0
0
0
40
0
0
0
0
% L
% Met:
0
0
7
14
0
0
0
0
67
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
7
% Q
% Arg:
0
0
0
0
14
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% S
% Thr:
7
0
67
0
0
14
0
0
0
0
0
0
0
0
0
% T
% Val:
60
0
0
0
67
0
7
7
0
0
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
14
0
54
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _