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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCEB3CL
All Species:
3.64
Human Site:
S222
Identified Species:
8.89
UniProt:
Q3SY89
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SY89
NP_001094287.1
546
59758
S222
P
Q
G
E
A
V
G
S
H
S
K
G
H
K
S
Chimpanzee
Pan troglodytes
XP_523920
753
84039
A414
L
G
D
K
Q
R
K
A
N
E
S
K
G
T
R
Rhesus Macaque
Macaca mulatta
XP_001090849
494
54833
S165
P
R
R
A
P
A
D
S
G
P
H
R
A
P
P
Dog
Lupus familis
XP_535361
848
95731
K509
L
G
E
K
G
L
K
K
N
D
P
K
S
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CB77
773
87159
K434
L
G
E
K
G
L
K
K
K
D
S
K
S
T
S
Rat
Rattus norvegicus
Q63187
773
87185
K434
L
G
E
K
G
L
K
K
K
D
S
K
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521771
748
82742
S281
K
E
R
E
G
G
G
S
R
K
R
P
L
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCP0
643
71143
S323
A
K
P
T
A
A
P
S
S
S
A
L
S
A
P
Honey Bee
Apis mellifera
XP_396851
659
74896
Q345
G
M
C
T
M
T
H
Q
N
L
S
K
K
R
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797640
908
98406
K365
I
S
S
Q
A
S
S
K
I
S
S
V
S
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.2
74.1
35.8
N.A.
36.7
37.3
N.A.
37
N.A.
N.A.
N.A.
N.A.
24.8
23.8
N.A.
23.7
Protein Similarity:
100
63.4
77.8
45.7
N.A.
47.7
48.5
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
43.5
42.4
N.A.
36.1
P-Site Identity:
100
0
13.3
0
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
0
N.A.
26.6
P-Site Similarity:
100
20
20
26.6
N.A.
20
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
30
20
0
10
0
0
10
0
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
0
30
0
0
0
0
0
% D
% Glu:
0
10
30
20
0
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
40
10
0
40
10
20
0
10
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
10
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
10
0
40
0
0
40
40
20
10
10
50
10
20
0
% K
% Leu:
40
0
0
0
0
30
0
0
0
10
0
10
10
0
0
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
20
% N
% Pro:
20
0
10
0
10
0
10
0
0
10
10
10
0
20
20
% P
% Gln:
0
10
0
10
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
20
0
0
10
0
0
10
0
10
10
0
10
10
% R
% Ser:
0
10
10
0
0
10
10
40
10
30
50
0
50
0
40
% S
% Thr:
0
0
0
20
0
10
0
0
0
0
0
0
0
40
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _