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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB3L1
All Species:
27.88
Human Site:
S49
Identified Species:
51.11
UniProt:
Q3SYE8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3SYE8
NP_005333
130
14606
S49
E
F
C
P
K
I
K
S
T
N
P
G
I
S
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103743
121
13584
S50
E
F
H
P
K
M
K
S
T
N
P
G
I
S
I
Dog
Lupus familis
XP_538194
201
23063
S113
E
F
R
P
K
I
K
S
T
N
P
G
I
S
I
Cat
Felis silvestris
Mouse
Mus musculus
O54879
200
22991
S113
E
F
R
P
K
I
K
S
T
N
P
G
I
S
I
Rat
Rattus norvegicus
P63159
215
24875
G115
E
Y
R
P
K
I
K
G
E
H
P
G
L
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509199
201
22939
S113
E
F
R
P
K
I
K
S
T
N
P
G
I
S
I
Chicken
Gallus gallus
P36194
201
22910
S112
E
F
R
P
K
I
K
S
T
N
P
G
I
S
I
Frog
Xenopus laevis
NP_001089163
201
23278
S113
E
F
R
P
K
I
K
S
T
N
P
G
I
S
I
Zebra Danio
Brachydanio rerio
NP_001116308
213
24538
A112
E
H
R
P
Q
I
K
A
Q
Y
P
S
L
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P40644
200
22815
S120
E
N
R
A
A
I
K
S
V
H
P
N
W
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
E61
E
F
R
K
E
F
K
E
K
N
P
K
N
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11632
93
10784
E34
A
Y
M
F
F
A
N
E
N
R
D
I
V
R
S
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
N43
F
A
N
E
Q
R
E
N
V
R
E
E
N
P
G
Conservation
Percent
Protein Identity:
100
N.A.
84.6
57.2
N.A.
57
42.3
N.A.
56.2
55.7
52.2
42.7
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
N.A.
85.3
59.2
N.A.
60.5
47.4
N.A.
57.7
57.2
56.2
47.8
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
N.A.
86.6
93.3
N.A.
93.3
60
N.A.
93.3
93.3
93.3
40
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
80
N.A.
93.3
93.3
93.3
60
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
38.8
N.A.
N.A.
30.7
33
Protein Similarity:
N.A.
50.3
N.A.
N.A.
41.5
45.3
P-Site Identity:
N.A.
33.3
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
40
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
85
0
0
8
8
0
8
16
8
0
8
8
0
0
0
% E
% Phe:
8
62
0
8
8
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
62
0
8
8
% G
% His:
0
8
8
0
0
0
0
0
0
16
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
70
0
0
0
0
0
8
54
0
70
% I
% Lys:
0
0
0
8
62
0
85
0
8
0
0
8
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
8
8
62
0
8
16
0
0
% N
% Pro:
0
0
0
70
0
0
0
0
0
0
85
0
0
8
0
% P
% Gln:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
70
0
0
8
0
0
0
16
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
62
0
0
0
8
0
70
16
% S
% Thr:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _