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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC88A All Species: 7.88
Human Site: S1837 Identified Species: 15.76
UniProt: Q3V6T2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3V6T2 NP_001129069.1 1871 216042 S1837 R L P I S V D S P P A A A D S
Chimpanzee Pan troglodytes XP_515485 2027 233227 S1837 R L P I S V D S P P A A A D S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_865410 1874 216370 V1838 D S R L P I S V D S P P A T A
Cat Felis silvestris
Mouse Mus musculus Q5SNZ0 1873 215900 S1839 R L P V S V D S S P P T A G S
Rat Rattus norvegicus XP_001065246 1872 215516 P1838 R L P V S V E P A P P P A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509593 1880 216999 Q1840 F L S K D S R Q P V S I D P S
Chicken Gallus gallus O42184 1433 161009 H1400 Q M L E E P P H S T Y H G S R
Frog Xenopus laevis P85120 2058 236320 P1840 A T S S S Q S P E P Q A L S P
Zebra Danio Brachydanio rerio XP_001921927 1997 227252 P1956 E Q R E A E S P L L K K A D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397453 1177 136326 L1144 G D D R R S I L L E Q T S R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782798 1863 213363 P1813 K G P S G K P P V P L P K S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 C911 V A L L V L A C V R M K R I A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 N.A. 97.1 N.A. 94.8 94.7 N.A. 90.8 20.2 43.8 45.7 N.A. N.A. 26.9 N.A. 36.4
Protein Similarity: 100 92.2 N.A. 98.7 N.A. 97.8 97.6 N.A. 95.3 39.7 63.7 63.8 N.A. N.A. 42.2 N.A. 56.1
P-Site Identity: 100 100 N.A. 6.6 N.A. 66.6 46.6 N.A. 20 0 20 13.3 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 26.6 N.A. 73.3 60 N.A. 26.6 13.3 20 26.6 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 9 0 9 0 17 25 50 0 17 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 0 9 0 25 0 9 0 0 0 9 25 0 % D
% Glu: 9 0 0 17 9 9 9 0 9 9 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 0 9 0 0 0 0 0 0 0 9 17 9 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 17 0 9 9 0 0 0 0 9 0 9 0 % I
% Lys: 9 0 0 9 0 9 0 0 0 0 9 17 9 0 0 % K
% Leu: 0 42 17 17 0 9 0 9 17 9 9 0 9 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 42 0 9 9 17 34 25 50 25 25 0 9 9 % P
% Gln: 9 9 0 0 0 9 0 9 0 0 17 0 0 0 0 % Q
% Arg: 34 0 17 9 9 0 9 0 0 9 0 0 9 9 17 % R
% Ser: 0 9 17 17 42 17 25 25 17 9 9 0 9 25 42 % S
% Thr: 0 9 0 0 0 0 0 0 0 9 0 17 0 9 9 % T
% Val: 9 0 0 17 9 34 0 9 17 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _