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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC88A All Species: 22.73
Human Site: S230 Identified Species: 45.45
UniProt: Q3V6T2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3V6T2 NP_001129069.1 1871 216042 S230 F L P H A S S S A Q S P C G S
Chimpanzee Pan troglodytes XP_515485 2027 233227 S230 F L P H A S S S A Q S P C G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_865410 1874 216370 S230 F L P H A S S S A Q S P C G S
Cat Felis silvestris
Mouse Mus musculus Q5SNZ0 1873 215900 S230 F L P H A S S S A Q S P C G S
Rat Rattus norvegicus XP_001065246 1872 215516 S230 F L P H A S S S A Q S P C G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509593 1880 216999 S229 H F L P H A S S A Q S P C G S
Chicken Gallus gallus O42184 1433 161009
Frog Xenopus laevis P85120 2058 236320 S233 P S P V K S S S P D T S A N M
Zebra Danio Brachydanio rerio XP_001921927 1997 227252 L229 S Q Q P S G L L G F P S P E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397453 1177 136326
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782798 1863 213363 L221 S Q A D G R V L S P S P S L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 N.A. 97.1 N.A. 94.8 94.7 N.A. 90.8 20.2 43.8 45.7 N.A. N.A. 26.9 N.A. 36.4
Protein Similarity: 100 92.2 N.A. 98.7 N.A. 97.8 97.6 N.A. 95.3 39.7 63.7 63.8 N.A. N.A. 42.2 N.A. 56.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 60 0 26.6 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 66.6 0 33.3 6.6 N.A. N.A. 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 42 9 0 0 50 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 42 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 9 0 0 9 0 0 0 0 50 0 % G
% His: 9 0 0 42 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 42 9 0 0 0 9 17 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 9 0 50 17 0 0 0 0 9 9 9 59 9 0 0 % P
% Gln: 0 17 9 0 0 0 0 0 0 50 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % R
% Ser: 17 9 0 0 9 50 59 59 9 0 59 17 9 0 50 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % T
% Val: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _