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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC88A All Species: 14.24
Human Site: Y1645 Identified Species: 28.48
UniProt: Q3V6T2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3V6T2 NP_001129069.1 1871 216042 Y1645 S G S S P I Q Y L K R Q T R S
Chimpanzee Pan troglodytes XP_515485 2027 233227 Y1645 S G S S P I Q Y L K R Q T R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_865410 1874 216370 Y1646 S G S S P I Q Y L K R Q T R S
Cat Felis silvestris
Mouse Mus musculus Q5SNZ0 1873 215900 L1647 G S S P I Q Y L K R Q T R S S
Rat Rattus norvegicus XP_001065246 1872 215516 L1646 G S S P V Q Y L K R Q T R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509593 1880 216999 Y1648 S S S S P I Q Y L K R N T R S
Chicken Gallus gallus O42184 1433 161009 E1208 L L E M K K R E S T L K K E I
Frog Xenopus laevis P85120 2058 236320 R1648 S R T P T R P R P G S P G S E
Zebra Danio Brachydanio rerio XP_001921927 1997 227252 T1764 V R L T D T S T P P S H S Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397453 1177 136326 Q952 R C S N L E F Q I N T L N Q R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782798 1863 213363 A1621 T E T D G P I A M A P H K S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 K719 L D E M D K E K W N L Q E S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 N.A. 97.1 N.A. 94.8 94.7 N.A. 90.8 20.2 43.8 45.7 N.A. N.A. 26.9 N.A. 36.4
Protein Similarity: 100 92.2 N.A. 98.7 N.A. 97.8 97.6 N.A. 95.3 39.7 63.7 63.8 N.A. N.A. 42.2 N.A. 56.1
P-Site Identity: 100 100 N.A. 100 N.A. 13.3 13.3 N.A. 86.6 0 6.6 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 26.6 26.6 N.A. 86.6 13.3 13.3 26.6 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 9 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 17 0 0 9 9 9 0 0 0 0 9 9 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 17 25 0 0 9 0 0 0 0 9 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % H
% Ile: 0 0 0 0 9 34 9 0 9 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 9 17 0 9 17 34 0 9 17 0 9 % K
% Leu: 17 9 9 0 9 0 0 17 34 0 17 9 0 0 0 % L
% Met: 0 0 0 17 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 17 0 9 9 0 0 % N
% Pro: 0 0 0 25 34 9 9 0 17 9 9 9 0 0 0 % P
% Gln: 0 0 0 0 0 17 34 9 0 0 17 34 0 17 0 % Q
% Arg: 9 17 0 0 0 9 9 9 0 17 34 0 17 34 9 % R
% Ser: 42 25 59 34 0 0 9 0 9 0 17 0 9 42 50 % S
% Thr: 9 0 17 9 9 9 0 9 0 9 9 17 34 0 9 % T
% Val: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 34 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _