KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM176B
All Species:
10.61
Human Site:
S254
Identified Species:
38.89
UniProt:
Q3YBM2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3YBM2
NP_001094781.1
270
29125
S254
K
R
L
L
G
E
N
S
V
P
P
S
P
S
R
Chimpanzee
Pan troglodytes
XP_001135990
233
25437
V218
R
L
L
G
E
N
S
V
P
P
S
P
S
R
E
Rhesus Macaque
Macaca mulatta
XP_001099742
268
28736
S252
K
R
L
L
G
E
N
S
V
P
P
S
P
S
R
Dog
Lupus familis
XP_853584
273
29113
S257
K
K
L
L
G
E
N
S
V
P
P
S
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1Q6
263
28349
H248
E
R
K
L
L
D
G
H
P
A
P
A
S
P
A
Rat
Rattus norvegicus
Q925D4
263
28467
G246
E
T
E
K
K
L
L
G
G
D
S
A
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519714
324
34414
S261
L
R
G
D
V
W
L
S
A
P
S
A
P
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
91.4
66.6
N.A.
53.3
51.1
N.A.
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.5
93.6
76.5
N.A.
67.4
67.7
N.A.
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
20
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
40
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
15
0
43
0
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
15
0
0
0
15
0
0
0
0
0
% D
% Glu:
29
0
15
0
15
43
0
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
15
43
0
15
15
15
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
43
15
15
15
15
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
15
15
58
58
15
15
29
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
43
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
29
72
58
15
72
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
58
0
0
0
0
0
0
0
0
0
0
0
15
29
% R
% Ser:
0
0
0
0
0
0
15
58
0
0
43
43
29
43
15
% S
% Thr:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
15
0
0
15
43
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _