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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARF All Species: 16.06
Human Site: S641 Identified Species: 39.26
UniProt: Q3YEC7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3YEC7 NP_060465.1 729 79549 S641 E A G P K E S S E E G K E G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093446 728 79391 S641 E A G P K E S S E E G K E G K
Dog Lupus familis XP_537794 1149 127779 S1062 E T S H K D I S D E D K E G K
Cat Felis silvestris
Mouse Mus musculus Q5U3K5 725 79813 S638 E M G P K E S S D E D R D S K
Rat Rattus norvegicus NP_001102043 731 80235 S644 E L G P K E S S E E D K D S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520022 199 23015 P133 P K V P T H V P V C V L G N Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700855 747 81591 E654 E A T P K T K E S S E D Q E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625002 676 76709 V600 V S V T S S N V H L E L L D N
Nematode Worm Caenorhab. elegans NP_509888 635 71742 K569 E E I D K I E K I T K K K K T
Sea Urchin Strong. purpuratus XP_001187240 929 101656 S789 V V Q D E D I S D C E T N T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.9 49.5 N.A. 81.4 81.4 N.A. 22.6 N.A. N.A. 60.3 N.A. N.A. 33.7 32.6 34.8
Protein Similarity: 100 N.A. 96.1 53.6 N.A. 87.5 87 N.A. 24.2 N.A. N.A. 72.5 N.A. N.A. 49.3 49.7 49.8
P-Site Identity: 100 N.A. 100 53.3 N.A. 60 73.3 N.A. 6.6 N.A. N.A. 26.6 N.A. N.A. 0 20 6.6
P-Site Similarity: 100 N.A. 100 66.6 N.A. 80 80 N.A. 6.6 N.A. N.A. 33.3 N.A. N.A. 13.3 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 20 0 0 30 0 30 10 20 10 10 % D
% Glu: 70 10 0 0 10 40 10 10 30 50 30 0 30 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 40 0 0 0 0 0 0 0 20 0 10 30 0 % G
% His: 0 0 0 10 0 10 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 20 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 70 0 10 10 0 0 10 50 10 10 50 % K
% Leu: 0 10 0 0 0 0 0 0 0 10 0 20 10 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 10 % N
% Pro: 10 0 0 60 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 10 10 0 10 10 40 60 10 10 0 0 0 20 10 % S
% Thr: 0 10 10 10 10 10 0 0 0 10 0 10 0 10 10 % T
% Val: 20 10 20 0 0 0 10 10 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _