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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM50 All Species: 13.94
Human Site: T46 Identified Species: 25.56
UniProt: Q3ZCQ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3ZCQ8 NP_001001563.1 353 39646 T46 E I G S R G S T K A Q G P Q Q
Chimpanzee Pan troglodytes XP_001138514 353 39658 T46 E I G S R G S T K T Q G P Q Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533672 356 40230 T46 E I G S R S G T K A Q A Q G P
Cat Felis silvestris
Mouse Mus musculus Q9D880 353 39758 S46 E I A N R G G S K A Q G P Q H
Rat Rattus norvegicus XP_001073346 381 42984 S74 E I A N R G G S K T Q G P Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NWD4 387 43862 K81 E G E D S G H K Q D E Q G E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4V8 428 49653 L111 N A P L L A K L F P Q T S P E
Honey Bee Apis mellifera XP_392112 387 45463 V67 I Q S S G G T V Q S L T Q D G
Nematode Worm Caenorhab. elegans Q22647 452 51360 L122 A I D E L N S L K D S L E K L
Sea Urchin Strong. purpuratus XP_794459 274 31551
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYE2 376 42621 F48 V T S T Q S M F S D F P P P N
Baker's Yeast Sacchar. cerevisiae Q02776 476 55080 G74 D V D E K G Q G K N E E T S G
Red Bread Mold Neurospora crassa Q874C1 540 60574 K70 P E P A E S E K A E Q K Q Q Q
Conservation
Percent
Protein Identity: 100 99.7 N.A. 92.9 N.A. 91.7 85.8 N.A. N.A. N.A. N.A. 62.7 N.A. 38.3 38.7 31.4 41
Protein Similarity: 100 99.7 N.A. 94.6 N.A. 95.7 88.9 N.A. N.A. N.A. N.A. 75.4 N.A. 50.7 56.3 48.2 56.9
P-Site Identity: 100 93.3 N.A. 60 N.A. 66.6 60 N.A. N.A. N.A. N.A. 13.3 N.A. 6.6 13.3 20 0
P-Site Similarity: 100 93.3 N.A. 60 N.A. 80 73.3 N.A. N.A. N.A. N.A. 33.3 N.A. 13.3 33.3 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 30.8 25.6 25.1
Protein Similarity: N.A. N.A. N.A. 46.5 41.1 39.4
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 20
P-Site Similarity: N.A. N.A. N.A. 20 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 8 0 8 0 0 8 24 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 8 0 0 0 0 0 24 0 0 0 8 8 % D
% Glu: 47 8 8 16 8 0 8 0 0 8 16 8 8 8 8 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 8 0 0 0 0 % F
% Gly: 0 8 24 0 8 54 24 8 0 0 0 31 8 8 16 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 16 % H
% Ile: 8 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 16 54 0 0 8 0 8 0 % K
% Leu: 0 0 0 8 16 0 0 16 0 0 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 16 0 8 0 0 0 8 0 0 0 0 8 % N
% Pro: 8 0 16 0 0 0 0 0 0 8 0 8 39 16 8 % P
% Gln: 0 8 0 0 8 0 8 0 16 0 54 8 24 39 24 % Q
% Arg: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 16 31 8 24 24 16 8 8 8 0 8 8 0 % S
% Thr: 0 8 0 8 0 0 8 24 0 16 0 16 8 0 0 % T
% Val: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _