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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KBTBD12 All Species: 16.97
Human Site: S228 Identified Species: 33.94
UniProt: Q3ZCT8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3ZCT8 NP_997218.2 623 71096 S228 R L E L V N P S F L R Q A L R
Chimpanzee Pan troglodytes XP_001141101 457 49844 G93 Q A H S V P R G T L S R V W D
Rhesus Macaque Macaca mulatta XP_001098649 623 71122 S228 R L E L V N P S F L R Q A L R
Dog Lupus familis XP_541739 623 71128 S228 R L E L I N P S F L R Q A L K
Cat Felis silvestris
Mouse Mus musculus Q9D618 625 71222 S226 R L E L I N A S F L R Q A L R
Rat Rattus norvegicus Q8K430 640 69714 K234 E F M L L P L K Q V L E L V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520793 361 41204
Chicken Gallus gallus XP_425160 619 70418 S228 R L V L V S P S F L M E A R K
Frog Xenopus laevis Q5U504 614 69682 D230 R F C L I P Q D Y I K N K V E
Zebra Danio Brachydanio rerio Q3ZB90 623 70237 D229 R L P L V G V D Y L K G T M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 I222 V G Q L V D I I C S D E L N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788235 595 67022 I213 T K D L I K L I E K D S L N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.5 98.2 94 N.A. 91.3 26 N.A. 47.5 74.9 24 56.5 N.A. 27.7 N.A. N.A. 28.2
Protein Similarity: 100 57.7 99.1 98.3 N.A. 95.3 44.5 N.A. 52.9 88.7 48.3 75.2 N.A. 46.5 N.A. N.A. 47.3
P-Site Identity: 100 13.3 100 86.6 N.A. 86.6 6.6 N.A. 0 60 13.3 33.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 93.3 33.3 N.A. 0 80 46.6 60 N.A. 33.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 9 0 0 0 0 0 42 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 17 0 0 17 0 0 0 9 % D
% Glu: 9 0 34 0 0 0 0 0 9 0 0 25 0 0 9 % E
% Phe: 0 17 0 0 0 0 0 0 42 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 9 0 9 0 0 0 9 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 34 0 9 17 0 9 0 0 0 0 9 % I
% Lys: 0 9 0 0 0 9 0 9 0 9 17 0 9 0 25 % K
% Leu: 0 50 0 84 9 0 17 0 0 59 9 0 25 34 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 9 0 0 9 0 % M
% Asn: 0 0 0 0 0 34 0 0 0 0 0 9 0 17 0 % N
% Pro: 0 0 9 0 0 25 34 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 0 0 9 0 9 0 0 34 0 0 0 % Q
% Arg: 59 0 0 0 0 0 9 0 0 0 34 9 0 9 25 % R
% Ser: 0 0 0 9 0 9 0 42 0 9 9 9 0 0 9 % S
% Thr: 9 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % T
% Val: 9 0 9 0 50 0 9 0 0 9 0 0 9 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _