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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KBTBD12 All Species: 24.24
Human Site: S312 Identified Species: 48.48
UniProt: Q3ZCT8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q3ZCT8 NP_997218.2 623 71096 S312 S R K T Y F I S S P K Y G E G
Chimpanzee Pan troglodytes XP_001141101 457 49844 W171 G S V Q A R S W P I A G P L R
Rhesus Macaque Macaca mulatta XP_001098649 623 71122 S312 S R K T Y F I S S P K Y G E G
Dog Lupus familis XP_541739 623 71128 S312 S R K T Y F V S S P K Y G E G
Cat Felis silvestris
Mouse Mus musculus Q9D618 625 71222 S310 S H K T Y F I S S P K Y G E G
Rat Rattus norvegicus Q8K430 640 69714 V345 A G P V L F A V G G G S L F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520793 361 41204 Y75 T Q R E V I L Y D V T A E S V
Chicken Gallus gallus XP_425160 619 70418 S312 T Q K T Y F I S S P K Y G E G
Frog Xenopus laevis Q5U504 614 69682 A323 I S D T G A V A Y D P S A N E
Zebra Danio Brachydanio rerio Q3ZB90 623 70237 T316 T G R T L F I T S P R Y G E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 P305 L L L P Q E R P L M Q G P R T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788235 595 67022 S291 E A R R Y H G S T F Y P G L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.5 98.2 94 N.A. 91.3 26 N.A. 47.5 74.9 24 56.5 N.A. 27.7 N.A. N.A. 28.2
Protein Similarity: 100 57.7 99.1 98.3 N.A. 95.3 44.5 N.A. 52.9 88.7 48.3 75.2 N.A. 46.5 N.A. N.A. 47.3
P-Site Identity: 100 0 100 93.3 N.A. 93.3 6.6 N.A. 0 86.6 6.6 53.3 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 0 100 100 N.A. 93.3 13.3 N.A. 26.6 100 20 80 N.A. 6.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 9 9 9 0 0 9 9 9 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 9 0 0 0 0 0 % D
% Glu: 9 0 0 9 0 9 0 0 0 0 0 0 9 50 9 % E
% Phe: 0 0 0 0 0 59 0 0 0 9 0 0 0 9 0 % F
% Gly: 9 17 0 0 9 0 9 0 9 9 9 17 59 0 42 % G
% His: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 9 % H
% Ile: 9 0 0 0 0 9 42 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 42 0 0 0 0 0 0 0 42 0 0 0 0 % K
% Leu: 9 9 9 0 17 0 9 0 9 0 0 0 9 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 9 9 0 0 0 9 9 50 9 9 17 0 0 % P
% Gln: 0 17 0 9 9 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 25 25 9 0 9 9 0 0 0 9 0 0 9 9 % R
% Ser: 34 17 0 0 0 0 9 50 50 0 0 17 0 9 0 % S
% Thr: 25 0 0 59 0 0 0 9 9 0 9 0 0 0 9 % T
% Val: 0 0 9 9 9 0 17 9 0 9 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 50 0 0 9 9 0 9 50 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _