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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHN1
All Species:
0.61
Human Site:
S46
Identified Species:
3.33
UniProt:
Q494U1
Number Species:
4
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q494U1
NP_001153656.1
663
71790
S46
P
G
P
E
A
A
R
S
G
D
A
A
A
N
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546726
602
65854
S17
A
P
R
R
L
R
A
S
F
S
R
K
P
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C886
359
39339
Rat
Rattus norvegicus
NP_001127995
615
67723
D30
S
L
K
G
N
R
E
D
S
A
R
K
L
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697734
700
79987
L48
S
N
S
I
I
N
I
L
C
T
V
T
P
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
66.9
N.A.
32.8
64.4
N.A.
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
74.5
N.A.
39.9
72
N.A.
N.A.
N.A.
N.A.
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
20
20
20
0
0
20
20
20
20
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
20
0
0
0
0
0
% D
% Glu:
0
0
0
20
0
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% F
% Gly:
0
20
0
20
0
0
0
0
20
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
20
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
0
0
0
40
0
0
40
% K
% Leu:
0
20
0
0
20
0
0
20
0
0
0
0
20
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
20
20
0
0
0
0
0
0
0
20
0
% N
% Pro:
20
20
20
0
0
0
0
0
0
0
0
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
20
20
0
40
20
0
0
0
40
0
0
20
0
% R
% Ser:
40
0
20
0
0
0
0
40
20
20
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
20
0
20
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _