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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC36A2 All Species: 20.91
Human Site: S254 Identified Species: 41.82
UniProt: Q495M3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q495M3 NP_861441.2 483 53216 S254 T Q E I P D P S R L P L V A S
Chimpanzee Pan troglodytes XP_518043 483 53240 S254 T Q E I P D P S R L P L V A S
Rhesus Macaque Macaca mulatta XP_001109854 481 52808 S252 T Q E I P D P S R L P L V A S
Dog Lupus familis XP_546292 483 52959 S254 A Q G I P D P S R L P L V A S
Cat Felis silvestris
Mouse Mus musculus Q8BHK3 478 52044 S249 I Q E I P D A S Q L P L V A S
Rat Rattus norvegicus Q8K415 481 52260 S252 I Q G I P D P S Q L P L V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512780 553 62169 R311 V R D M T D P R S L P A V A G
Chicken Gallus gallus XP_417200 504 55771 R262 V R D I A D P R K L P P M V G
Frog Xenopus laevis Q4KL91 522 58726 R282 I R N L S D P R T L P L G T S
Zebra Danio Brachydanio rerio Q5SPB1 504 55813 N267 S Q P P Q T N N S T D E E C C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34479 460 51320 D225 V Q Q P N Q W D K L P A A T N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50944 713 80007 M473 D L M G T P A M G V V Y G L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 90.8 84.6 N.A. 81.5 81.1 N.A. 48.2 51.1 48.2 20.4 N.A. N.A. N.A. 26.7 N.A.
Protein Similarity: 100 99.5 93.7 91 N.A. 89.6 90.6 N.A. 64 68.8 65.7 41.8 N.A. N.A. N.A. 49 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 40 33.3 40 6.6 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 60 60 53.3 20 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 17 0 0 0 0 17 9 59 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % C
% Asp: 9 0 17 0 0 75 0 9 0 0 9 0 0 0 0 % D
% Glu: 0 0 34 0 0 0 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 9 0 0 0 0 9 0 0 0 17 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % K
% Leu: 0 9 0 9 0 0 0 0 0 84 0 59 0 9 0 % L
% Met: 0 0 9 9 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 0 0 9 0 9 0 9 9 0 0 0 0 0 0 17 % N
% Pro: 0 0 9 17 50 9 67 0 0 0 84 9 0 0 0 % P
% Gln: 0 67 9 0 9 9 0 0 17 0 0 0 0 0 0 % Q
% Arg: 0 25 0 0 0 0 0 25 34 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 9 0 0 50 17 0 0 0 0 0 59 % S
% Thr: 25 0 0 0 17 9 0 0 9 9 0 0 0 17 0 % T
% Val: 25 0 0 0 0 0 0 0 0 9 9 0 59 9 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _