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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC36A3
All Species:
9.7
Human Site:
S459
Identified Species:
19.39
UniProt:
Q495N2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495N2
NP_001138489.1
470
51735
S459
Y
E
L
P
Q
P
I
S
H
S
M
A
N
S
T
Chimpanzee
Pan troglodytes
XP_001167827
470
51770
S459
Y
E
L
P
Q
P
I
S
H
S
M
A
N
S
T
Rhesus Macaque
Macaca mulatta
XP_001109621
470
51885
N459
Y
E
L
T
Q
P
I
N
H
S
M
A
N
S
T
Dog
Lupus familis
XP_546293
474
52629
N463
Y
E
L
I
Q
P
I
N
H
S
I
A
N
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q811P0
477
53049
H466
Y
E
M
T
Q
Q
T
H
F
Y
M
A
N
S
T
Rat
Rattus norvegicus
Q4V8B1
477
52832
R466
Y
E
M
T
Q
Q
S
R
F
P
M
L
N
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512780
553
62169
P529
E
E
I
I
Y
P
P
P
T
S
L
I
N
T
T
Chicken
Gallus gallus
XP_417200
504
55771
S480
E
E
I
I
Y
P
A
S
T
V
L
A
N
T
T
Frog
Xenopus laevis
Q4KL91
522
58726
S500
E
E
M
I
Y
P
I
S
Y
V
P
P
N
V
S
Zebra Danio
Brachydanio rerio
XP_687732
468
51466
A457
T
S
I
Q
E
I
V
A
R
N
G
D
R
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34479
460
51320
H449
A
G
V
Y
T
N
I
H
A
I
I
Q
S
F
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50944
713
80007
L694
K
P
M
L
D
T
I
L
I
F
F
G
I
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
85.4
N.A.
73.3
73.1
N.A.
43.9
48
45
54.4
N.A.
N.A.
N.A.
24.4
N.A.
Protein Similarity:
100
99.7
97.8
92.1
N.A.
83.4
82.8
N.A.
60.9
65.2
63.2
70.2
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
53.3
46.6
N.A.
33.3
40
33.3
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
60
53.3
N.A.
53.3
60
53.3
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
9
9
0
0
50
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
25
75
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
17
9
9
0
0
9
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
34
0
0
0
0
9
0
% H
% Ile:
0
0
25
34
0
9
59
0
9
9
17
9
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
34
9
0
0
0
9
0
0
17
9
0
0
0
% L
% Met:
0
0
34
0
0
0
0
0
0
0
42
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
17
0
9
0
0
75
0
9
% N
% Pro:
0
9
0
17
0
59
9
9
0
9
9
9
0
0
0
% P
% Gln:
0
0
0
9
50
17
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% R
% Ser:
0
9
0
0
0
0
9
34
0
42
0
0
9
50
25
% S
% Thr:
9
0
0
25
9
9
9
0
17
0
0
0
0
17
67
% T
% Val:
0
0
9
0
0
0
9
0
0
17
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
9
25
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _