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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC36A3 All Species: 17.58
Human Site: S461 Identified Species: 35.15
UniProt: Q495N2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q495N2 NP_001138489.1 470 51735 S461 L P Q P I S H S M A N S T G V
Chimpanzee Pan troglodytes XP_001167827 470 51770 S461 L P Q P I S H S M A N S T G V
Rhesus Macaque Macaca mulatta XP_001109621 470 51885 S461 L T Q P I N H S M A N S T G V
Dog Lupus familis XP_546293 474 52629 S465 L I Q P I N H S I A N S T G V
Cat Felis silvestris
Mouse Mus musculus Q811P0 477 53049 Y468 M T Q Q T H F Y M A N S T R V
Rat Rattus norvegicus Q4V8B1 477 52832 P468 M T Q Q S R F P M L N S T N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512780 553 62169 S531 I I Y P P P T S L I N T T Q S
Chicken Gallus gallus XP_417200 504 55771 V482 I I Y P A S T V L A N T T E S
Frog Xenopus laevis Q4KL91 522 58726 V502 M I Y P I S Y V P P N V S H S
Zebra Danio Brachydanio rerio XP_687732 468 51466 N459 I Q E I V A R N G D R H N S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34479 460 51320 I451 V Y T N I H A I I Q S F S Q P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50944 713 80007 F696 M L D T I L I F F G I A S M L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.7 85.4 N.A. 73.3 73.1 N.A. 43.9 48 45 54.4 N.A. N.A. N.A. 24.4 N.A.
Protein Similarity: 100 99.7 97.8 92.1 N.A. 83.4 82.8 N.A. 60.9 65.2 63.2 70.2 N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: 100 100 86.6 80 N.A. 46.6 40 N.A. 26.6 33.3 26.6 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 53.3 46.6 N.A. 46.6 53.3 46.6 33.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 9 0 0 50 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 17 9 9 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 9 0 0 0 34 0 % G
% His: 0 0 0 0 0 17 34 0 0 0 0 9 0 9 0 % H
% Ile: 25 34 0 9 59 0 9 9 17 9 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 34 9 0 0 0 9 0 0 17 9 0 0 0 0 9 % L
% Met: 34 0 0 0 0 0 0 0 42 0 0 0 0 9 0 % M
% Asn: 0 0 0 9 0 17 0 9 0 0 75 0 9 9 0 % N
% Pro: 0 17 0 59 9 9 0 9 9 9 0 0 0 0 9 % P
% Gln: 0 9 50 17 0 0 0 0 0 9 0 0 0 17 0 % Q
% Arg: 0 0 0 0 0 9 9 0 0 0 9 0 0 9 0 % R
% Ser: 0 0 0 0 9 34 0 42 0 0 9 50 25 9 25 % S
% Thr: 0 25 9 9 9 0 17 0 0 0 0 17 67 0 9 % T
% Val: 9 0 0 0 9 0 0 17 0 0 0 9 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 25 0 0 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _