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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
16.67
Human Site:
Y263
Identified Species:
33.33
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
Y263
L
G
M
P
S
R
E
Y
Y
F
N
G
G
S
N
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
Y265
L
G
M
P
S
R
D
Y
Y
F
N
G
G
R
N
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
T235
S
R
D
Y
Y
E
C
T
G
I
Y
K
E
A
C
Dog
Lupus familis
XP_546737
807
92419
Y291
L
G
M
P
S
R
E
Y
Y
F
N
E
G
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
Y249
L
G
M
P
S
R
E
Y
Y
F
Q
E
D
N
N
Rat
Rattus norvegicus
P0C1T0
774
89178
E258
T
L
G
M
P
S
R
E
Y
Y
F
K
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
G233
S
R
D
Y
Y
F
N
G
G
N
Y
Q
R
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
Y239
L
G
M
P
S
R
D
Y
Y
L
S
D
G
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
Q336
V
N
I
L
Q
M
D
Q
L
Q
Y
A
L
P
S
Honey Bee
Apis mellifera
XP_392502
776
89056
L263
S
S
A
N
I
L
Q
L
D
Q
M
Q
V
A
L
Nematode Worm
Caenorhab. elegans
O16796
848
97043
D333
A
L
G
R
G
T
R
D
Y
Y
L
N
T
T
L
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
S251
V
L
Q
I
D
Q
S
S
L
G
I
S
S
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
86.6
0
93.3
N.A.
73.3
6.6
N.A.
N.A.
0
N.A.
60
N.A.
0
0
6.6
0
P-Site Similarity:
100
93.3
6.6
93.3
N.A.
80
20
N.A.
N.A.
0
N.A.
80
N.A.
26.6
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
0
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
17
0
9
0
25
9
9
0
0
9
9
9
0
% D
% Glu:
0
0
0
0
0
9
25
9
0
0
0
17
17
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
34
9
0
0
0
0
% F
% Gly:
0
42
17
0
9
0
0
9
17
9
0
17
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
9
0
0
0
0
9
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% K
% Leu:
42
25
0
9
0
9
0
9
17
9
9
0
9
0
17
% L
% Met:
0
0
42
9
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
9
0
0
9
25
9
0
17
34
% N
% Pro:
0
0
0
42
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
0
9
9
9
9
0
17
9
17
0
0
0
% Q
% Arg:
0
17
0
9
0
42
17
0
0
0
0
0
9
17
9
% R
% Ser:
25
9
0
0
42
9
9
9
0
0
9
9
9
17
17
% S
% Thr:
9
0
0
0
0
9
0
9
0
0
0
0
9
9
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
17
0
0
42
59
17
25
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _