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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM60
All Species:
0
Human Site:
T250
Identified Species:
0
UniProt:
Q495X7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.63
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495X7
NP_689833.1
471
55114
T250
Q
S
N
L
E
L
L
T
Q
A
K
S
M
H
H
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
K260
Q
S
G
F
E
M
L
K
D
V
K
S
T
L
E
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
Q250
G
S
M
M
D
L
L
Q
G
V
D
G
I
I
K
Dog
Lupus familis
XP_538824
488
56376
K260
Q
S
G
F
E
M
L
K
D
V
K
S
T
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI40
466
54180
V245
A
I
H
E
R
S
D
V
T
L
L
R
A
Y
H
Rat
Rattus norvegicus
Q6MFZ5
488
56376
K260
Q
S
G
F
E
M
L
K
D
V
K
S
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509541
527
60558
K307
Q
S
A
V
E
L
L
K
G
I
K
S
T
L
S
Chicken
Gallus gallus
NP_001092822
588
66812
K371
Q
P
V
L
E
F
L
K
D
V
M
S
I
I
S
Frog
Xenopus laevis
Q91431
610
69096
I385
L
T
D
I
K
T
F
I
D
K
C
Q
E
Q
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.1
30.3
43.2
N.A.
52.4
42.8
N.A.
44.2
28.9
25.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.4
53.1
60.8
N.A.
70.6
60.4
N.A.
60.7
46.2
42.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
20
40
N.A.
6.6
40
N.A.
46.6
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
40
46.6
N.A.
20
46.6
N.A.
53.3
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
0
0
12
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
12
0
12
0
12
0
56
0
12
0
0
0
0
% D
% Glu:
0
0
0
12
67
0
0
0
0
0
0
0
12
0
34
% E
% Phe:
0
0
0
34
0
12
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
34
0
0
0
0
0
23
0
0
12
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
23
% H
% Ile:
0
12
0
12
0
0
0
12
0
12
0
0
23
23
0
% I
% Lys:
0
0
0
0
12
0
0
56
0
12
56
0
0
0
12
% K
% Leu:
12
0
0
23
0
34
78
0
0
12
12
0
0
45
0
% L
% Met:
0
0
12
12
0
34
0
0
0
0
12
0
12
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
0
0
0
0
0
0
12
12
0
0
12
0
12
12
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
67
0
0
0
12
0
0
0
0
0
67
0
0
23
% S
% Thr:
0
12
0
0
0
12
0
12
12
0
0
0
45
0
0
% T
% Val:
0
0
12
12
0
0
0
12
0
56
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _