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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDNF
All Species:
19.09
Human Site:
Y178
Identified Species:
38.18
UniProt:
Q49AH0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AH0
NP_001025125.2
187
20964
Y178
I
Q
E
L
A
P
K
Y
A
A
T
H
P
K
T
Chimpanzee
Pan troglodytes
XP_507666
187
21018
Y178
I
Q
E
L
A
P
K
Y
A
A
T
H
P
K
T
Rhesus Macaque
Macaca mulatta
XP_001088321
187
20989
Y178
I
Q
E
L
A
P
K
Y
A
A
T
H
P
K
T
Dog
Lupus familis
XP_848954
165
18581
A157
T
E
L
A
P
K
Y
A
A
A
H
P
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC36
187
21013
Y178
I
R
E
L
A
P
K
Y
V
E
I
Y
P
Q
T
Rat
Rattus norvegicus
P0C5I0
187
21342
Y178
I
K
E
L
A
P
K
Y
V
E
T
R
P
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515575
162
18511
A154
K
E
L
T
P
K
Y
A
A
T
S
P
R
S
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116753
182
20358
H170
I
Q
E
V
A
P
K
H
S
A
S
E
H
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ63
173
20118
K165
I
K
R
I
E
E
L
K
P
K
Y
S
R
S
E
Honey Bee
Apis mellifera
XP_625023
175
20050
Y167
I
E
E
L
K
P
K
Y
S
H
S
A
K
S
E
Nematode Worm
Caenorhab. elegans
Q9N3B0
168
18950
K160
I
K
R
I
E
E
L
K
P
K
Y
V
K
E
E
Sea Urchin
Strong. purpuratus
XP_001178263
163
18873
A155
E
E
L
K
P
K
Y
A
K
K
Q
P
K
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.9
75.9
N.A.
77.5
80.7
N.A.
57.2
N.A.
N.A.
47.5
N.A.
44.3
42.7
42.7
43.3
Protein Similarity:
100
99.4
98.9
78
N.A.
86
87.6
N.A.
67.9
N.A.
N.A.
65.2
N.A.
58.8
62
58.8
64.1
P-Site Identity:
100
100
100
13.3
N.A.
60
66.6
N.A.
6.6
N.A.
N.A.
46.6
N.A.
6.6
40
6.6
0
P-Site Similarity:
100
100
100
20
N.A.
80
80
N.A.
20
N.A.
N.A.
80
N.A.
20
60
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
50
0
0
25
42
42
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
34
59
0
17
17
0
0
0
17
0
9
0
17
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
9
25
9
0
0
% H
% Ile:
75
0
0
17
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
9
25
0
9
9
25
59
17
9
25
0
0
34
25
0
% K
% Leu:
0
0
25
50
0
0
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
25
59
0
0
17
0
0
25
42
0
0
% P
% Gln:
0
34
0
0
0
0
0
0
0
0
9
0
0
17
0
% Q
% Arg:
0
9
17
0
0
0
0
0
0
0
0
9
17
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
17
0
25
9
0
25
0
% S
% Thr:
9
0
0
9
0
0
0
0
0
9
34
0
0
9
42
% T
% Val:
0
0
0
9
0
0
0
0
17
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
25
50
0
0
17
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _