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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDNF
All Species:
21.82
Human Site:
Y48
Identified Species:
43.64
UniProt:
Q49AH0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AH0
NP_001025125.2
187
20964
Y48
K
E
F
L
N
R
F
Y
K
S
L
I
D
R
G
Chimpanzee
Pan troglodytes
XP_507666
187
21018
Y48
K
E
F
L
N
R
F
Y
K
S
L
I
D
R
G
Rhesus Macaque
Macaca mulatta
XP_001088321
187
20989
Y48
K
E
F
L
N
R
F
Y
K
S
L
I
D
R
G
Dog
Lupus familis
XP_848954
165
18581
A31
R
F
Y
N
S
L
I
A
R
G
V
N
F
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC36
187
21013
Y48
K
E
F
L
D
R
F
Y
N
S
L
L
S
R
G
Rat
Rattus norvegicus
P0C5I0
187
21342
Y48
K
E
F
L
N
R
F
Y
N
S
L
L
T
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515575
162
18511
S28
R
L
Y
N
S
L
L
S
K
D
I
H
F
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116753
182
20358
Y39
V
G
F
L
G
R
L
Y
N
S
L
V
I
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ63
173
20118
A39
V
K
T
V
R
R
F
A
D
S
L
D
D
S
T
Honey Bee
Apis mellifera
XP_625023
175
20050
N39
N
T
V
E
R
F
V
N
T
L
S
E
D
V
K
Nematode Worm
Caenorhab. elegans
Q9N3B0
168
18950
A34
K
V
L
D
D
V
M
A
K
V
P
A
G
D
K
Sea Urchin
Strong. purpuratus
XP_001178263
163
18873
T29
K
H
L
E
S
L
M
T
N
E
D
R
K
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.9
75.9
N.A.
77.5
80.7
N.A.
57.2
N.A.
N.A.
47.5
N.A.
44.3
42.7
42.7
43.3
Protein Similarity:
100
99.4
98.9
78
N.A.
86
87.6
N.A.
67.9
N.A.
N.A.
65.2
N.A.
58.8
62
58.8
64.1
P-Site Identity:
100
100
100
0
N.A.
73.3
80
N.A.
13.3
N.A.
N.A.
46.6
N.A.
33.3
6.6
13.3
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
86.6
N.A.
40
N.A.
N.A.
53.3
N.A.
46.6
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
25
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
17
0
0
0
9
9
9
9
42
9
0
% D
% Glu:
0
42
0
17
0
0
0
0
0
9
0
9
0
0
9
% E
% Phe:
0
9
50
0
0
9
50
0
0
0
0
0
17
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
0
9
0
0
9
0
50
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
25
9
0
0
% I
% Lys:
59
9
0
0
0
0
0
0
42
0
0
0
9
0
17
% K
% Leu:
0
9
17
50
0
25
17
0
0
9
59
17
0
0
9
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
17
34
0
0
9
34
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
17
59
0
0
9
0
0
9
0
50
0
% R
% Ser:
0
0
0
0
25
0
0
9
0
59
9
0
9
34
0
% S
% Thr:
0
9
9
0
0
0
0
9
9
0
0
0
9
0
9
% T
% Val:
17
9
9
9
0
9
9
0
0
9
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _