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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDNF All Species: 25.76
Human Site: Y83 Identified Species: 51.52
UniProt: Q49AH0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q49AH0 NP_001025125.2 187 20964 Y83 G K E N R L C Y Y L G A T K D
Chimpanzee Pan troglodytes XP_507666 187 21018 Y83 G K E N R L C Y Y L G A T K D
Rhesus Macaque Macaca mulatta XP_001088321 187 20989 Y83 G K E N R L C Y Y L G A T K D
Dog Lupus familis XP_848954 165 18581 T66 L C Y Y L G A T K D A A T K I
Cat Felis silvestris
Mouse Mus musculus Q8CC36 187 21013 Y83 G K E N R L C Y Y L G A T T D
Rat Rattus norvegicus P0C5I0 187 21342 Y83 G K E N R L C Y Y L G A T K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515575 162 18511 T63 L C Y Y L G A T S D A A T K I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116753 182 20358 Y74 G K E N R L C Y Y L G A S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XZ63 173 20118 Y74 K E H R F C Y Y L G G L E E S
Honey Bee Apis mellifera XP_625023 175 20050 L74 E N R F C Y Y L G G L E E S A
Nematode Worm Caenorhab. elegans Q9N3B0 168 18950 I69 E N K F C F Y I G A L P E S A
Sea Urchin Strong. purpuratus XP_001178263 163 18873 T64 F C Y Y M G G T E D A A T G M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.9 75.9 N.A. 77.5 80.7 N.A. 57.2 N.A. N.A. 47.5 N.A. 44.3 42.7 42.7 43.3
Protein Similarity: 100 99.4 98.9 78 N.A. 86 87.6 N.A. 67.9 N.A. N.A. 65.2 N.A. 58.8 62 58.8 64.1
P-Site Identity: 100 100 100 20 N.A. 93.3 100 N.A. 20 N.A. N.A. 86.6 N.A. 13.3 0 0 13.3
P-Site Similarity: 100 100 100 20 N.A. 93.3 100 N.A. 20 N.A. N.A. 93.3 N.A. 26.6 0 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 17 0 0 9 25 75 0 0 17 % A
% Cys: 0 25 0 0 17 9 50 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 50 % D
% Glu: 17 9 50 0 0 0 0 0 9 0 0 9 25 9 0 % E
% Phe: 9 0 0 17 9 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 0 0 25 9 0 17 17 59 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 17 % I
% Lys: 9 50 9 0 0 0 0 0 9 0 0 0 0 50 0 % K
% Leu: 17 0 0 0 17 50 0 9 9 50 17 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 17 0 50 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 9 50 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 9 0 0 0 9 25 9 % S
% Thr: 0 0 0 0 0 0 0 25 0 0 0 0 67 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 25 25 0 9 25 59 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _