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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM135B
All Species:
9.09
Human Site:
S288
Identified Species:
22.22
UniProt:
Q49AJ0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AJ0
NP_056996.2
1406
155770
S288
E
T
L
S
Q
L
C
S
E
L
Q
M
L
N
N
Chimpanzee
Pan troglodytes
XP_519975
1191
131551
H124
T
T
Y
L
T
Q
E
H
H
T
L
R
V
R
R
Rhesus Macaque
Macaca mulatta
XP_001089896
1308
144316
H241
T
Y
L
T
Q
E
H
H
T
L
R
V
R
R
F
Dog
Lupus familis
XP_539175
1123
125047
D56
R
L
V
H
L
Q
G
D
L
D
A
Q
L
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAI6
1403
155506
S288
E
T
L
S
Q
L
C
S
E
L
Q
M
L
N
N
Rat
Rattus norvegicus
XP_001072719
1403
155444
S288
E
T
L
S
Q
L
C
S
E
L
Q
M
L
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510578
1506
167802
E278
A
R
L
A
E
L
C
E
E
V
K
K
M
E
N
Chicken
Gallus gallus
XP_425944
1420
158886
A288
D
T
L
S
Q
F
C
A
E
L
Q
L
L
S
N
Frog
Xenopus laevis
Q641I1
1376
154423
N287
R
T
L
S
Q
L
C
N
Q
L
Q
L
L
S
D
Zebra Danio
Brachydanio rerio
XP_001343106
1413
158576
I289
E
T
L
N
Q
L
T
I
E
L
Q
L
Q
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84
90.9
68.7
N.A.
81.1
80.8
N.A.
37.7
62.3
53.3
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.3
91.6
72.3
N.A.
86.9
87
N.A.
56.5
74
68
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
20
6.6
N.A.
100
100
N.A.
33.3
66.6
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
40
26.6
N.A.
100
100
N.A.
66.6
93.3
93.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
20
% D
% Glu:
40
0
0
0
10
10
10
10
60
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
10
20
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% K
% Leu:
0
10
80
10
10
60
0
0
10
70
10
30
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
30
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
0
0
30
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
70
20
0
0
10
0
60
10
10
0
0
% Q
% Arg:
20
10
0
0
0
0
0
0
0
0
10
10
10
20
10
% R
% Ser:
0
0
0
50
0
0
0
30
0
0
0
0
0
40
0
% S
% Thr:
20
70
0
10
10
0
10
0
10
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
10
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _