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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRY2 All Species: 30.3
Human Site: S530 Identified Species: 51.28
UniProt: Q49AN0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q49AN0 NP_001120929.1 593 66947 S530 P S C V E D L S H P V A E P S
Chimpanzee Pan troglodytes XP_001160595 593 66872 S530 P S C V E D L S H P V A E P S
Rhesus Macaque Macaca mulatta XP_001113162 593 66839 S530 P S C V E D L S H P V A E P S
Dog Lupus familis XP_540761 593 66822 S530 P S C V E D L S N P V A E P S
Cat Felis silvestris
Mouse Mus musculus Q9R194 592 66832 S529 P S C V E D L S H P V A E P G
Rat Rattus norvegicus Q923I8 594 67204 S529 P S C V E D L S H P V A E P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507425 582 65716 S517 P S C V E D L S S A A A E S G
Chicken Gallus gallus Q8QG60 582 66078 S520 P S C V E D L S G P V T D S A
Frog Xenopus laevis Q75WS4 523 60626 L463 A S L A H A N L S L G E T Y P
Zebra Danio Brachydanio rerio Q4KML2 520 59903 A460 S N S A L S H A Q V S L N Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77059 542 62494 Q482 M S A E Q Q E Q Y E C L I G V
Honey Bee Apis mellifera NP_001077099 570 65246 N509 K Q V Y Q Q L N K Y R G N G V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785873 516 59965 S456 P F L K N F P S K Y I F E P W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96524 612 69439 A512 D S F E A L G A N T I K E P G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 96.4 N.A. 94.5 93.7 N.A. 88.1 85.8 23.4 25.6 N.A. 37.4 62.3 N.A. 57.6
Protein Similarity: 100 99.6 99.4 97.4 N.A. 96.2 95.7 N.A. 90.8 91 40.9 42.5 N.A. 53.2 74.5 N.A. 69.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 66.6 66.6 6.6 0 N.A. 6.6 6.6 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 66.6 80 6.6 20 N.A. 20 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 15 8 8 0 15 0 8 8 50 0 0 8 % A
% Cys: 0 0 58 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 0 0 0 58 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 15 58 0 8 0 0 8 0 8 65 0 0 % E
% Phe: 0 8 8 0 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 8 0 8 8 0 15 29 % G
% His: 0 0 0 0 8 0 8 0 36 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 15 0 8 0 0 % I
% Lys: 8 0 0 8 0 0 0 0 15 0 0 8 0 0 0 % K
% Leu: 0 0 15 0 8 8 65 8 0 8 0 15 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 8 8 15 0 0 0 15 0 0 % N
% Pro: 65 0 0 0 0 0 8 0 0 50 0 0 0 58 8 % P
% Gln: 0 8 0 0 15 15 0 8 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 79 8 0 0 8 0 65 15 0 8 0 0 15 29 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 8 8 0 8 % T
% Val: 0 0 8 58 0 0 0 0 0 8 50 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 8 0 0 0 0 8 15 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _