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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRY2 All Species: 28.79
Human Site: S65 Identified Species: 48.72
UniProt: Q49AN0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q49AN0 NP_001120929.1 593 66947 S65 P W F A A S S S V G I N R W R
Chimpanzee Pan troglodytes XP_001160595 593 66872 S65 P W F A A S S S V G I N R W R
Rhesus Macaque Macaca mulatta XP_001113162 593 66839 S65 P W F A A S S S V G I N R W R
Dog Lupus familis XP_540761 593 66822 S65 P W F A A S S S V G I N R W R
Cat Felis silvestris
Mouse Mus musculus Q9R194 592 66832 S64 P W F A A S S S V G I N R W R
Rat Rattus norvegicus Q923I8 594 67204 S64 P W F A A S S S V G I N R W R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507425 582 65716 S52 P W F A A S S S V G I N R W R
Chicken Gallus gallus Q8QG60 582 66078 A55 P W F A A S S A V G I N R W R
Frog Xenopus laevis Q75WS4 523 60626 Y45 Y C F D P R H Y V G T H Y F N
Zebra Danio Brachydanio rerio Q4KML2 520 59903 R42 P L Y C F D P R H Y Q G T Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77059 542 62494 N51 G E S A G T K N V G Y N R M R
Honey Bee Apis mellifera NP_001077099 570 65246 N64 P W F A G S T N I G I N K W R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785873 516 59965 E38 H D N P A L K E G L K S A S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96524 612 69439 W54 Y P G R A S R W W M K Q S L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 96.4 N.A. 94.5 93.7 N.A. 88.1 85.8 23.4 25.6 N.A. 37.4 62.3 N.A. 57.6
Protein Similarity: 100 99.6 99.4 97.4 N.A. 96.2 95.7 N.A. 90.8 91 40.9 42.5 N.A. 53.2 74.5 N.A. 69.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 20 6.6 N.A. 40 66.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 33.3 20 N.A. 53.3 93.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 72 72 0 0 8 0 0 0 0 8 0 8 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 72 0 8 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 8 0 15 0 0 0 8 79 0 8 0 0 8 % G
% His: 8 0 0 0 0 0 8 0 8 0 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 65 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 15 0 0 0 15 0 8 0 0 % K
% Leu: 0 8 0 0 0 8 0 0 0 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 15 0 0 0 72 0 0 8 % N
% Pro: 72 8 0 8 8 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 0 0 8 0 8 8 8 0 0 0 0 65 0 72 % R
% Ser: 0 0 8 0 0 72 58 50 0 0 0 8 8 8 0 % S
% Thr: 0 0 0 0 0 8 8 0 0 0 8 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 72 0 0 0 0 0 0 % V
% Trp: 0 65 0 0 0 0 0 8 8 0 0 0 0 65 0 % W
% Tyr: 15 0 8 0 0 0 0 8 0 8 8 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _