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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY2
All Species:
31.82
Human Site:
Y253
Identified Species:
53.85
UniProt:
Q49AN0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AN0
NP_001120929.1
593
66947
Y253
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Chimpanzee
Pan troglodytes
XP_001160595
593
66872
Y253
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Rhesus Macaque
Macaca mulatta
XP_001113162
593
66839
Y253
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Dog
Lupus familis
XP_540761
593
66822
Y253
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R194
592
66832
Y252
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Rat
Rattus norvegicus
Q923I8
594
67204
Y252
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507425
582
65716
Y240
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Chicken
Gallus gallus
Q8QG60
582
66078
Y243
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Frog
Xenopus laevis
Q75WS4
523
60626
R211
Q
D
P
L
T
D
P
R
T
A
F
P
C
S
G
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
D208
G
Q
T
E
P
L
D
D
C
R
S
A
F
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
A230
W
R
G
G
E
T
Q
A
L
L
L
L
D
E
R
Honey Bee
Apis mellifera
NP_001077099
570
65246
F252
R
K
A
W
V
A
S
F
G
R
P
K
M
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
K204
I
D
P
N
H
E
D
K
Y
G
I
P
T
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
I230
E
F
I
E
K
Q
L
I
D
Y
A
K
N
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
96.4
N.A.
94.5
93.7
N.A.
88.1
85.8
23.4
25.6
N.A.
37.4
62.3
N.A.
57.6
Protein Similarity:
100
99.6
99.4
97.4
N.A.
96.2
95.7
N.A.
90.8
91
40.9
42.5
N.A.
53.2
74.5
N.A.
69.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
6.6
N.A.
0
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
13.3
20
N.A.
6.6
80
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
65
0
0
65
0
8
0
8
8
8
0
0
58
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% C
% Asp:
0
15
0
0
0
8
15
8
8
0
0
0
8
0
0
% D
% Glu:
8
0
0
15
8
8
0
0
58
0
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
8
0
8
8
0
0
0
0
8
8
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
65
0
0
8
0
0
8
0
0
0
15
0
0
8
% K
% Leu:
0
0
0
8
0
8
8
0
8
8
8
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
65
0
0
% M
% Asn:
0
0
0
8
0
0
58
0
0
0
0
0
8
58
0
% N
% Pro:
0
0
15
0
8
0
8
0
0
0
65
15
0
8
8
% P
% Gln:
8
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
65
8
0
0
0
0
0
8
0
72
0
58
0
0
8
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
8
0
0
15
0
% S
% Thr:
0
0
8
0
8
8
0
0
8
0
0
0
8
8
0
% T
% Val:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
65
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _