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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C5orf22
All Species:
16.36
Human Site:
S221
Identified Species:
40
UniProt:
Q49AR2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AR2
NP_060826.2
442
49967
S221
T
C
L
E
P
S
C
S
C
S
S
E
N
Q
E
Chimpanzee
Pan troglodytes
XP_517821
442
49983
S221
T
C
L
E
P
S
C
S
H
S
S
E
N
Q
E
Rhesus Macaque
Macaca mulatta
XP_001086409
442
50107
S221
T
C
L
E
P
S
R
S
C
S
S
E
N
Q
E
Dog
Lupus familis
XP_855465
482
54089
S260
T
C
L
E
Q
S
C
S
C
F
S
E
S
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC1
442
49411
S221
A
C
Q
E
P
S
C
S
R
S
G
G
Q
Q
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418996
538
59622
N305
V
Q
H
A
S
A
L
N
R
A
K
M
L
P
E
Frog
Xenopus laevis
Q6PAE6
423
47851
G209
T
S
E
S
S
E
D
G
L
V
K
A
T
C
S
Zebra Danio
Brachydanio rerio
Q7SZF1
439
49547
D219
T
A
K
K
K
A
D
D
G
S
T
S
Y
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524154
470
53922
L242
H
D
A
D
N
E
S
L
N
P
N
E
F
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781846
578
64288
Y287
N
C
P
T
Q
K
P
Y
S
G
T
E
Q
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.2
82.5
N.A.
78.5
N.A.
N.A.
N.A.
55.3
62.4
54.7
N.A.
22.5
N.A.
N.A.
36.1
Protein Similarity:
100
99.7
98.8
86.7
N.A.
86.1
N.A.
N.A.
N.A.
65.6
75.5
69.4
N.A.
37.6
N.A.
N.A.
52.4
P-Site Identity:
100
93.3
93.3
80
N.A.
53.3
N.A.
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
53.3
N.A.
N.A.
N.A.
26.6
6.6
33.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
20
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
60
0
0
0
0
40
0
30
0
0
0
0
10
0
% C
% Asp:
0
10
0
10
0
0
20
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
50
0
20
0
0
0
0
0
60
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
10
10
10
0
0
0
% G
% His:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
10
10
10
0
0
0
0
20
0
0
0
0
% K
% Leu:
0
0
40
0
0
0
10
10
10
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
10
10
0
10
0
30
0
0
% N
% Pro:
0
0
10
0
40
0
10
0
0
10
0
0
0
10
0
% P
% Gln:
0
10
10
0
20
0
0
0
0
0
0
0
20
50
0
% Q
% Arg:
0
0
0
0
0
0
10
0
20
0
0
0
0
10
0
% R
% Ser:
0
10
0
10
20
50
10
50
10
50
40
10
10
0
20
% S
% Thr:
60
0
0
10
0
0
0
0
0
0
20
0
10
0
20
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _